An aneurysmal bone cyst at T1 treated with bone grafts containing calcitonin and methylprednisolone.

An aneurysmal bone cyst at T1 treated with bone grafts containing calcitonin and methylprednisolone. J Orthop Surg (Hong Kong). 2019 May-Aug;27(2):2309499019839626 Authors: Okuda A, Shigematsu H, Iwata E, Tanaka M, Morimoto Y, Masuda K, Ohbayashi C, Tanaka Y Abstract Aneurysmal bone cysts (ABCs) rarely trigger pathological fractures. Various surgical and nonsurgical treatments have been reported for this condition. Herein, we present the examination findings and treatment for a 15-year-old girl who initially presented with adolescent idiopathic scoliosis and mild back pain, but subsequently experienced severe back pain. Magnetic resonance imaging revealed an ABC at T1, with an associated pathological fracture. We successfully treated the patient using posterior fixation with instrumentation, curettage, and bone grafts combined with calcitonin and methylprednisolone (mPSL). At 3 years post-surgery, there was no ABC recurrence and only mild back pain persisted. To our knowledge, this is the first report of open surgery (curettage and fixation) with local intralesional administration of calcitonin and mPSL for an ABC-induced pathological spinal fracture. We believe that this treatment is an effective option for ABCs associated with a pathological spinal fracture. PMID: 30943849 [PubMed - in process]
Source: Journal of Orthopaedic Surgery - Category: Orthopaedics Authors: Tags: J Orthop Surg (Hong Kong) Source Type: research