Births from embryos with highly elevated levels of mitochondrial dna

ConclusionsMeasurement of mtDNA copy number might not provide any advantage to embryo prioritization and could lead to de-selection of blastocysts that would result in healthy pregnancies and births. Furthermore, the quantitation of mitochondrial functional output in a model of cellular stress might suggest that mitochondria are not clear targets for biomarker identification as it relates to blastocyst viability. Any suggested link between mtDNA levels, mitochondria, or their output with blastocyst transfer outcome requires further validation.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research