Sequential organ failure assessment score is an excellent operationalization of disease severity of adult patients with hospitalized community acquired pneumonia – results from the prospective observational PROGRESS study

CAP (Community acquired pneumonia) is frequent, with a high mortality rate and a high burden on health care systems. Development of predictive biomarkers, new therapeutic concepts, and epidemiologic research r...
Source: Critical Care - Category: Intensive Care Authors: Tags: Research Source Type: research

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AbstractLung ultrasound (US) cannot be considered a new diagnostic imaging technique anymore, with some articles dating back 50  years. The question that hovers over it recently is why it is still not widely accepted, like chest radiography. So, have we wasted a lot of time without using lung US, or are we wasting our time using lung US? The main goals of this article are to underline all the advantages, potentials and reas ons to use lung US in everyday clinical practice, but also to address the main concerns linked to this imaging tool. From the standpoint of an experienced pediatric radiologist from a tertiary heal...
Source: Pediatric Radiology - Category: Radiology Source Type: research
This cohort study compares 30-day mortality among adult patients hospitalized for pneumonia receiving empirical anti –methicillin-resistant Staphylococcus aureus (MRSA) therapy vs standard empirical antibiotic regimens.
Source: JAMA Internal Medicine - Category: Internal Medicine Source Type: research
The prevailing practice in many hospitals is to give immediate, often broad-spectrum, antibiotics to all hospitalized patients with possible infections. Two interlinked factors drive this practice: (1) clinicians fear that any delay in appropriate antibiotics may increase patients ’ risk for worse outcomes including death, and (2) it is uncomfortable to withhold antibiotics from a patient who may have an infection, even if the likelihood of infection is low; doing something feels more responsive, responsible, and patient-centric than doing nothing. The net result, however, is widespread use of antibiotics, much of wh...
Source: JAMA Internal Medicine - Category: Internal Medicine Source Type: research
Walking pneumonia causes milder symptoms than pneumonia, including being tired and having a sore throat, fever, and cough, the CDC says. Symptoms can be mild, more like a bad cold, but it can still lead to pneumonia.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
The purpose of this study was evaluating the efficacy and safety of intravenous (IV) ampicillin–sulbactam plus nebulized colistin in the treatment of Ventilator-Associated Pneumonia (VAP) caused by MDR Acinetobacter (MDRA)in ICU patients as an alternative to IV plus nebulized colistin. In this single-blinded RCT, one group received IV colistin and another group IV ampicillin–sulbactam (16 and 12 patients from total 28 patients, respectively) for 14 days or since clinical response. Both groups received nebulized colistin by mesh nebulizer. There were no statistically significant differences between the 2 groups ...
Source: Iranian Journal of Pharmaceutical Research - Category: Drugs & Pharmacology Source Type: research
Authors: Lin X, Gong Z, Xiao Z, Xiong J, Fan B, Liu J Abstract Since the 2019 novel coronavirus (2019-nCoV or officially named by the World Health Organization as COVID-19) outbreak in Wuhan, Hubei Province, China in 2019, there have been a few reports of its imaging findings. Here, we report two confirmed cases of 2019-nCoV pneumonia with chest computed tomography findings of multiple regions of patchy consolidation and ground-glass opacities in both lungs. These findings were characteristically located along the bronchial bundle or subpleural lungs. PMID: 32056397 [PubMed - as supplied by publisher]
Source: Korean Journal of Radiology - Category: Radiology Tags: Korean J Radiol Source Type: research
Authors: Lee KS PMID: 32056396 [PubMed - as supplied by publisher]
Source: Korean Journal of Radiology - Category: Radiology Tags: Korean J Radiol Source Type: research
Authors: Oztek Celebi FZ, Fettah A, Yesil S, Yoldas T, Tanir G, Akcaboy M, Senel S Abstract Chlamydophila pneumoniae, a common cause of respiratory tract infections, rarely leads to serious conditions. A 13-year-old boy with serologically confirmed C. pneumoniae infection presented with pneumonia complicated by pericardial and bilateral pleural effusions. He had a large haemorrhagic pericardial effusion from which 1000 ml of fluid was aspirated over 10 days and a right haemorrhagic pleural effusion which required a chest drain and the removal of 700 ml over 5 days. The addition of clarithromycin...
Source: Paediatrics and international child health - Category: Pediatrics Tags: Paediatr Int Child Health Source Type: research
Authors: Lim J, Jeon S, Shin HY, Kim MJ, Seong YM, Lee WJ, Choe KW, Kang YM, Lee B, Park SJ Abstract Since mid-December of 2019, coronavirus disease 2019 (COVID-19) infection has been spreading from Wuhan, China. The confirmed COVID-19 patients in South Korea are those who came from or visited China. As secondary transmissions have occurred and the speed of transmission is accelerating, there are rising concerns about community infections. The 54-year old male is the third patient diagnosed with COVID-19 infection in Korea. He is a worker for a clothing business and had mild respiratory symptoms and intermittent fe...
Source: Journal of Korean Medical Science - Category: Biomedical Science Tags: J Korean Med Sci Source Type: research
Publication date: Available online 14 February 2020Source: Journal of Hospital InfectionAuthor(s): Hao Jin, Ligong Lu, Junwei Liu, Min Cui
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
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