Discussion

Dr Daniel Kreisel (St Louis, Mo). Congratulations on your nice presentation and thank you for sending me the paper in advance. Your group published this model in The American Journal of Transplantation in 2016, and this current work represents a very nice and elegant model to study the responses of cells isolated from lung transplant recipients in vivo. Your results suggest that the development of transplant arteriosclerosis in humanized mice correlates with the development of chronic lung allograft dysfunction (CLAD) in human lung recipients and that regulatory T cells may inhibit the development of graft pathology.
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research