Low expression of pentraxin 3 and nuclear factor-like 2 implying a relatively longer overall survival time in gliomas.

In conclusion, we demonstrated that high PTX3 expression implied aggressive tumor behavior and shorter survival time in glioma patients. In addition, our results also showed that gliomas with low PTX3 and Nrf2 immunohistochemical expression could imply a longer overall survival time. Therefore, the combination of lower PTX3 and Nrf2 immunohistochemical expression may be important in offering a better prognosis in gliomas, although the detailed mechanism is yet to be elucidated. PMID: 30942197 [PubMed - in process]
Source: The Chinese Journal of Physiology - Category: Physiology Tags: Chin J Physiol Source Type: research