Undernourishment and recurrent seizures early in life impair Long-Term Potentiation and alter NMDAR and AMPAR expression in rat hippocampus.

In conclusion, our study showed impaired LTP after undernourishment and recurrent seizures early in life, together with differential expression of NDMA expression in the hippocampus during adulthood. PMID: 30940500 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30940500?dopt=Abstract

Source: International Journal of Developmental Neuroscience - March 29, 2019 Category: Neuroscience Authors: Wearick-Silva LE, Sebben AD, Costa-Ferro ZSM, Marinowic DR, Nunes ML Tags: Int J Dev Neurosci Source Type: research