The development of an extended normothermic ex vivo reperfusion model of the sheep uterus to evaluate organ quality after cold ischemia in relation to uterus transplantation

ConclusionsWe developed a novelex vivo sheep uterus model for prolonged perfusion. This model proved to be able to distinguish reperfusion injury ‐related differences associated to organ preservation. The experimental setup is a platform that can be used to conduct further studies on uterine ischemia‐ and reperfusion injury that may lead to improved human uterus transplantation protocols.This article is protected by copyright. All rights reserved.
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: Original Research Article Source Type: research

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CONCLUSIONS No significant association was found between ACE SNPs rs4316, rs4331, rs4343, or rs4362 and NOA in the Chinese Han population of Northeast China. PMID: 31198195 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
ConclusionWhile components of a mixture of lipids and lipophilic micronutrients were associated with live birth outcomes following IVF, a larger investigation is necessary to fully evaluate the potential clinical implications.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
Authors: Mencaglia L, Cerboneschi M, Ciociola F, Ricci S, Mancioppi I, Ambrosino V, Ferrandi C, Strozzi F, Piffanelli P, Grasselli A Abstract Female fertility plays a decisive role in the reproduction of mammals, with related issues that include oocyte or embryo quality, establishment of pregnancy, and the physiology of the tissues that contribute to reproduction and metabolic disorders associated with reproductive failure. Although reproductive failure may be attributed to various factors in different species, female infertility is largely controlled by a number of molecular signals that can be regulated in a cycl...
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research
In Britain, children of infertile couples who have used a sperm or egg donor will soon be able to find out the name and recent address of the donor.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
AbstractPurpose of ReviewThe classification of morphologically normal sperm has been progressively redefined. Concurrently, our understanding of the significance of sperm morphology in relation to male factor infertility has evolved. In this review, we will discuss the evolution of sperm morphology assessment and factors that contribute to its measurement variability. We will examine the impact of sperm morphology on natural pregnancy, IUI, IVF, and ICSI outcomes.Recent FindingsThere is a lack of consensus on sperm morphology classification, technique, and inter-observer grading variability. Current evidence suggests sperm...
Source: Current Urology Reports - Category: Urology & Nephrology Source Type: research
Derin Gebhardt, 37, from Roundup, Montana, was diagnosed in May 2017 with a pituitary tumor, which was causing a decrease in normal levels of sex hormones and behind his infertility.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Publication date: Available online 13 June 2019Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Leila Kohan, Omid Tabiee, Neda SepahiAbstractObjectiveMale infertility is a multifactorial disease resulting from the interaction between the genetic and environmental factors. Spermatogenic failure accounts for more than half of male infertility cases. Heat shock proteins (HSPs) are the molecular chaperones that are involved in different developmental stages of spermatogenesis. The current study was planned to investigate the role of HSPA1L rs2227956 and HSPA1B rs1061581 gene polymorphis...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Authors: Campo-Engelstein L, Chen D, Baratz AB, Johnson EK, Finlayson C Abstract Fertility preservation has become more common for various populations, including oncology patients, transgender individuals, and women who are concerned about age-related infertility. Little attention has been paid to fertility preservation for patients with differences/disorders of sex development (DSD). Our goal in this article is to address specific ethical considerations that are unique to this patient population. To this end, we present a hypothetical DSD case. We then explore ethical considerations related to patient's age, risk ...
Source: Journal of Clinical Ethics - Category: Medical Ethics Tags: J Clin Ethics Source Type: research
ConclusionThe study indicates that weight loss may prevent obesity ‐associated adverse health effects due to reduction of overall DNA damage.
Source: Molecular Nutrition and Food Research - Category: Food Science Authors: Tags: Research Article Source Type: research
With Father’s Day mere days away, we’re hearing more advertisements for outdoor grills and golf clubs, sailboats and fishing gear. As an infertility counselor, I am glad that Father’s Day is not welcomed with the gush of sentiment that envelops Mother’s Day. Still, a day dedicated to celebrating fatherhood can be difficult for any number of people. Among them are men and women who lost their fathers when they were quite young, and those who have experienced rocky relationships with their dads. There are men who have regrets about their own role as fathers, and older gay men who missed out on fatherh...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Fertility Infertility Men's Health Mental Health Relationships Source Type: blogs
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