Mapping the neuroanatomy of functional decline in Alzheimer ’s disease from basic to advanced activities of daily living

ConclusionsThe association between ADL domains and neurodegeneration in AD follows a traceable neuropathological pathway which involves different neural networks. This the first evidence of ADL phenotypes in AD characterised by specific patterns of functional decline and well-defined neuropathological changes. The identification of such phenotypes can yield functional biomarkers for dementias such as AD.
Source: Journal of Neurology - Category: Neurology Source Type: research