A school-aged boy with super-refractory status epilepticus secondary to cortical dysplasia treated with dexmedetomidine

Publication date: Available online 3 April 2019Source: Journal of Clinical NeuroscienceAuthor(s): John R. Malta, Jonathan Greco, Mauro Lodolo, Suman GhoshAbstractThis case report details a novel approach to the management of super-refractory status epilepticus (SRSE) in a boy with new-onset seizures progressing to SRSE. After exhausting multiple medications, dexmedetomidine, an α2-adrenoreceptor agonist used for sedation, stopped his SRSE. Dexmedetomidine provides a unique mechanism of action to treat this condition. Further studies are needed to determine its role in SRSE.
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research