Update on the Clinical Approach to Spatial Neglect

This article addresses the implementation gap in identifying and treating spatial neglect, to reduce disability and improve healthcare costs and burden.Recent FindingsProfessional organizations published recommendations to implement spatial neglect care. Physicians can lead an interdisciplinary team: functionally relevant spatial neglect assessment, evidence-based spatial retraining, and integrated spatial and vision interventions can optimize outcomes. Research also strongly suggests spatial neglect adversely affects motor systems. Spatial neglect therapy might thus “kick-start” rehabilitation and improve paralysis recovery.SummaryClinicians can implement new techniques to detect spatial neglect and lead interdisciplinary teams to promote better, integrated spatial neglect care. Future studies of brain imaging biomarkers to detect spatial neglect, and real-world applicability of prism adaptation treatment, are needed.
Source: Current Neurology and Neuroscience Reports - Category: Neuroscience Source Type: research

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Central neuropathic pain can be difficult to treat and, subsequently, cause a great amount of disability and distress to patients, which limits quality of life. Common etiologies include the following: stroke, spinal cord injury, multiple sclerosis, infection, vasculitis, and malignancy. This case is a description of an 18-yr-old male patient diagnosed with a grade IV diffuse glioma who experienced severe neuropathic pain refractory to first-line treatment options including the following: gabapentinoids, tricyclic antidepressants, and selective serotonin and norepinephrine reuptake inhibitors. The patient remained on high-...
Source: American Journal of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Case Report Source Type: research
This article is part of the Special Issue “Seizures &Stroke”
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
By STEVEN MERAHN, MD In 1807, in an effort to spite the British and French for shipping interference (and forced recruitment of American citizens into military service), the United States Congress passed an Embargo Act, effectively shutting down trade with these two countries. Britain and France quickly found other trading partners; the US, then limited in our capacity to sell products outside our borders, was left with a devastated economy and a gaping hole in our face. It took only weeks before Congress passed a loophole; they repealed the act within 15 months of its passing. It was a great lesson in unintended co...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Health Policy Politics Uncategorized Health care debate Health Care Reform Steven Merahn universal healthcare Source Type: blogs
Research reveals stroke survivors who completed group aerobic exercise programs similar to cardiac rehabilitation programs significantly improved aerobic endurance and walking ability
Source: Disabled World - Category: Disability Tags: Aerobics Source Type: news
CONCLUSION: Despite their brevity, both generic ICF-based tools seemed useful in finding disabilities for patient- and family-centred goal-setting and service-planning after subacute rehabilitation. PMID: 31402390 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - Category: Rehabilitation Tags: J Rehabil Med Source Type: research
Background: Cerebral small vessel disease (SVD) is associated with cognitive decline, depression, increased mortality and disability in stroke patients. MRI-visible perivascular spaces (PVS) are a sensitive neuroimaging marker of SVD. We aimed to explore the risk factors and associations with other SVD markers of PVS in two topographical regions (in the basal ganglia [BG] and centrum semiovale [CS]) in a cohort of spontaneous intracerebral hemorrhage (ICH) patients. Method: We included 306 consecutive patients from a prospective spontaneous ICH cohort. We rated perivascular spaces, white matter hyperintensities (WMH), ce...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
CONCLUSIONS: In 2014, there were 28,212,820 (2.02% AIS and 5.50% LDs) hospitalizations. LDs patients had higher prevalence and odds of having AIS compared with non-LDs. Between 2003-2014, of the total 4,224,924 AIS hospitalizations, 451,645 (10.69%) had LDs. Patients with LDs had lower percentages and odds of mortality, risk of death, major/extreme disability, discharge to nursing facility, and complications including epilepsy, stroke-associated pneumonia, GI-bleeding and hemorrhagic-transformation compared to non-LDs. Although LDs are risk factors for AIS, concurrent LDs in AIS is not only associated with lower mortality ...
Source: Medicina (Kaunas) - Category: Universities & Medical Training Authors: Tags: Medicina (Kaunas) Source Type: research
In conclusion, this study indicated that LncRNA-ROR could promote the cerebral H/R injury by inhibiting the expression of miR-135a-5p through upregulating the expression of ROCK1/2. And, miR-135a-5p overexpression could improve the cerebral H/R injury by inhibiting the expression of ROCK1/2. PMID: 31419405 [PubMed - as supplied by publisher]
Source: Experimental and Molecular Pathology - Category: Pathology Authors: Tags: Exp Mol Pathol Source Type: research
Conclusions: Intraarterial infusion of HUCB-derived cells inversed lateralized performance of learning task resulting from focal brain damage. The inversion was not visible in any other of the used motor as well as cognitive tests. The observed behavioral effect of cell infusion was also not related to the range of the brain damage. Our findings contribute to describing the effects of systemic treatment with the HUCB-derived cells on functional recovery following focal brain injury.
Source: Frontiers in Neurology - Category: Neurology Source Type: research
AbstractIschaemic stroke represents one of the main causes of disability. According to the broad investigations, it is widely assumed that the contribution of inflammatory mediators is strongly involved in its pathogenesis. Hence, it seems that stroke treatment needs more efficient and inflammatory-targeted compounds to modulate inflammatory-related pathways. Such strategies paved the way to achieve better clinical outcomes along with conventional therapies. Boswellic acids (BAs), the main bioactive compounds ofBoswellia sp. resin; are triterpenoids with well-documented anti-inflammatory properties. Compared with NSAIDs, B...
Source: Inflammopharmacology - Category: Drugs & Pharmacology Source Type: research
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