Untargeted LC –MS metabolomic studies of Asteraceae species to discover inhibitors of Leishmania major dihydroorotate dehydrogenase

ConclusionOur approach was validated for (1) the discovery ofLmDHODH inhibitors or interesting starting points for the optimization of new leishmanicides from Asteraceae species and (2) the prediction of extracts from untested species, classifying them as active or inactive.
Source: Metabolomics - Category: Biology Source Type: research