Biomimetic nanochannel membrane for cascade response of borate and cis-hydroxyl compounds: an IMP logic gate device

Publication date: Available online 2 April 2019Source: Chinese Chemical LettersAuthor(s): Meitao Deng, Meng Yang, Yaqing Xu, Yuqiong Sun, Qing Wang, Jianbo Liu, Jin Huang, Xiaohai Yang, Kemin WangABSTRACTBiomimetic nanodevice is an important branch to expand the potential applications of artificial nanochannels. Here, we constructed nanochannels for cascade response of borate and cis-hydroxyl compounds by modifying the nanochannels of track-etched polycarbonate (TEPC) membranes with polyvinyl alcohol (PVA). Firstly, borate bound to PVA and increased the negative charge density on the surface of the nanochannels, which obstructed the transport of 1,5-naphthalene disulfonate (NDS2-). Subsequently, the addition of cis-hydroxyl compounds induced leaving of borate due to the stronger binding affinities between borate and cis-hydroxyl compounds, which reduced the negative charge density on nanochannels and then enhanced the transport of NDS2-. The cascade response of the nanochannels also accord with the properties of IMP (implication) logic gate. In addition, such nanochannels showed good reproducibility and reversibility. Therefore, this cascade response model based on nanochannels has the potential to be used as switches in area of actuators and biosensors, and is also expected to be used to understand the interaction of substances in nanoscale and simulate the physiological functions of boron.Graphical abstractBiomimetic cascade response of borate and cis-hydroxyl compounds in ...
Source: Chinese Chemical Letters - Category: Chemistry Source Type: research