Coeliac disease

Coeliac disease (CD) is a common, chronic, immune-mediated small bowel enteropathy resulting from gluten exposure in genetically susceptible individuals. Considerable clinical and immunopathological heterogeneity is seen in newly diagnosed patients, and the diagnosis is not always straightforward even for experienced physicians. Population screening using tissue transglutaminase 2 has revealed a higher prevalence of seropositivity than previously appreciated. There is a wide differential diagnosis for mucosal villous atrophy, crypt hyperplasia and increased intraepithelial lymphocyte concentrations.
Source: Medicine - Category: Internal Medicine Authors: Tags: Malabsorption Source Type: research

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CONCLUSIONS: DI is frequent in Sjögrenser patients, mainly in the form of autoimmune disorders, and seem to be associated with a more severe phenotype. Our results suggest that DI should be evaluated in pSS patients, especially those with more severe disease. PMID: 33025900 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Beneficial Microbes, Ahead of Print.
Source: Beneficial Microbes - Category: Gastroenterology Authors: Source Type: research
Authors: Quintarelli L, Corrá A, Maglie R, Antiga E, Caproni M PMID: 33016667 [PubMed - as supplied by publisher]
Source: Giornale Italiano di Dermatologia e Venereologia - Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research
We describe the case of a 16-year-old boy with a medical history of allergic asthma, celiac disease, and known food-induced allergy for fish, fresh milk, peanuts, hazelnuts, walnuts, apples, kiwis, and peaches. Acute onset of dyspnea followed by cyanosis of the lips and respiratory failure was described immediately after having an ice cream sandwich. Unsuccessful rescues were immediately attempted with oral administration of betamethasone, intramuscular injection of adrenaline, and cardiopulmonary resuscitation. A complete post-mortem examination was performed. Serum dosage of mast cell beta-tryptase from femoral blood det...
Source: International Journal of Immunopathology and Pharmacology - Category: Allergy & Immunology Tags: Int J Immunopathol Pharmacol Source Type: research
Conclusions Despite the high prevalence of alarm symptoms at diagnosis, coincident major UGI endoscopic findings are rare in adult coeliac disease. These results may be relevant for future developments in coeliac disease diagnosis in adults.
Source: European Journal of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research
No abstract available
Source: European Journal of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Letters to the Editor Source Type: research
Celiac disease is an autoimmune condition characterized by an inappropriate immune reaction against gluten. It classically presents as chronic diarrhea, bloating, and nausea in addition to malabsorption sympto...
Source: BMC Gastroenterology - Category: Gastroenterology Authors: Tags: Case report Source Type: research
CONCLUSION: In cSLE, PA is associated with more hospitalizations and aggressive immunotherapy use. Although lupus disease activity improved over time, patients' QoL neither improved over time nor differed by having other autoimmune disease. Prospective, case-control, long-term follow-up studies on cSLE are needed to validate our results. MESH KEY INDEXING TERMS: Pediatric systemic lupus erythematosus; Autoimmune diseases; Outcome assessment. PMID: 33016198 [PubMed - as supplied by publisher]
Source: Lupus - Category: Rheumatology Authors: Tags: Lupus Source Type: research
Publication date: Available online 2 October 2020Source: International Journal of Surgery Case ReportsAuthor(s): Gregory G. Tsiotos, Nikiforos Ballian, Fotios Milas, Panoraia Ziogou, Ilias Athanasiadis
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Conditions:   Intestinal Disease;   Inflammatory Bowel Diseases;   Crohn Disease;   Ulcer;   Celiac Disease Intervention:   Device: SV-3 Capsule Endoscopy Sponsors:   Capso Vision, Inc.;   Generic Devices Consulting, Inc. Completed
Source: - Category: Research Source Type: clinical trials
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