Safety, Diagnostic Accuracy, and Effects of Endoscopic Ultrasound Fine-needle Aspiration on Detection of Extra-vascular Migratory Metastases

Tumor cells can migrate via diminutive perivascular cuffing to distant sites along blood vessels to formextra-vascular migratory metastases (EVMM). These metastases are usually identified during surgery or autopsies. We aimed to evaluate the feasibility and safety of endoscopic ultrasound fine-needle aspiration (EUS-FNA) of perivascular soft-tissue cuffs to detect EVMM. We compared findings from EUS with those from non-invasive cross-sectional imaging (reference standard) of patients who underwent EUS-FNA to assess suspected EVMM and studied the effects on pancreatic tumor staging and determination of resectability.

Source: Clinical Gastroenterology and Hepatology - April 2, 2019 Category: Gastroenterology Authors: Tarun Rustagi, Ferga C. Gleeson, Suresh T. Chari, Heidi D. Lehrke, Naoki Takahashi, Thomas M. Malikowski, Barham K. Abu Dayyeh, Vinay Chandrasekhara, Prasad G. Iyer, Michael L. Kendrick, Randall K. Pearson, Bret T. Petersen, Elizabeth Rajan, Rory L. Smoot Source Type: research