Joint consensus on anesthesia in urologic and gynecologic robotic surgery: specific issues in management from a task force of the SIAARTI, SIGO, and SIU.
CONCLUSIONS: This consensus document provides guidance for the management of urologic and gynecologic patients scheduled for robotic-assisted surgery. Moreover, the identified unmet needs highlight the requirement for further prospective randomized studies. PMID: 30938121 [PubMed - as supplied by publisher]
A new study reveals that macrophages release a growth factor that promotes the generation and activation of nerve cells to cause endometriosis pain.
Small study suggests botulinum toxin may be potential treatment.
Olympic champion cyclist Elinor Barker tells BBC Sport Wales the pain caused by endometriosis almost forced her to quit the sport.
(NIH/National Institute of Neurological Disorders and Stroke) Pelvic pain associated with endometriosis often becomes chronic and can persist (or recur) following surgical and hormonal interventions. According to results published in Regional Anesthesia&Pain Medicine, treating pelvic floor muscle spasm with botulinum toxin may relieve pain and improve quality of life. The study was conducted by scientists at the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health.
ConclusionsThese findings show the utility and reliability of multiplex arrays in deciphering new biomarker panels for disease detection and may offer clues for understanding this mysterious disease.
Conclusion: These findings are important for counselling adolescents regarding this common presentation.What is Known:•Dysmenorrhoea is the most common gynaecological complaint for adolescentsWhat is New:•Dysmenorrhoea from adolescence resolves in 1 in 4 of young women and no adolescent characteristics predict severe or very severe pain with menstruation in adults.•Only 1 in 5 of women were found to have endometriosis (all mild disease), despite a mean of 10 years of preceding dysmenorrhoea.
Conditions: Endometriosis; Chronic Pain; Quality of Life Interventions: Device: Radiofrequency A; Device: Radiofrequency B Sponsor: Hospital Clinic of Barcelona Recruiting
Conclusions: Abdominal wall endometriosis is the presence of ectopic endometrial tissue in any layer of the abdominal wall. Patients with this diagnosis are referred to the general surgeon presenting a tumor, however, the preoperative diagnosis rate is erroneous in most cases. Abdominal wall ultrasound is useful in diagnosis; tomography and magnetic resonance determine the extent of the disease. The treatment must be related to the extension of the disease and its recurrence is associated with the presence of positive margins. PMID: 31264985 [PubMed - in process]
Endometriosis has long been considered a disease localized to the pelvis with pain as the primary manifestation. Often overlooked are the multiple subtle manifestations of the disease. The immediate need for pain relief typically is the primary focus of the patient and physician. Numerous symptoms in addition to pain contribute to the burden of this disease. Here Surrey et al. (1) focus on one symptom that is frequently disruptive to patients with endometriosis. Fatigue is infrequently used as an end-point in clinical trials, however fatigue can be a debilitating symptom of endometriosis.
CONCLUSION: Altogether, EPHA3 could potentially promote the autophagy and apoptosis of macrophages in endometriosis via inhibition of the mTOR signaling pathway, highlighting the potential of EPHA3 as the target to treat endometriosis. PMID: 31262977 [PubMed - as supplied by publisher]