Comparison of the Effects of High-Fat Diet on Energy Flux in Mice Using Two Multiplexed Metabolic Phenotyping Systems.

CONCLUSIONS: Design differences quantitatively impact the assessment of metabolic end points and thus the qualitative interpretation of various interventions. Importantly, current multiplexed systems remain blind to multiple additional end points, including digestive efficiency and selected forms of energy flux (nitrogenous, anaerobic, etc.), that account for a physiologically and/or pathophysiologically significant fraction of total energy flux.
PMID: 30938081 [PubMed - as supplied by publisher]

Source: Obesity - April 1, 2019 Category: Eating Disorders & Weight Management Authors: Soto JE, Burnett CML, Ten Eyck P, Abel ED, Grobe JL Tags: Obesity (Silver Spring) Source Type: research