Dexamethasone protects the glycocalyx on the kidney microvascular endothelium during severe acute pancreatitis.

CONCLUSIONS: Dexamethasone protects the endothelial glycocalyx from inflammatory degradation possibly initiated by TNF-α during SAP. This is might be a significant discovery that helps to prevent tissue edema and hypoperfusion in the future.
PMID: 30932380 [PubMed - in process]

Source: J Zhejiang Univ Sci ... - March 31, 2019 Category: Science Authors: Yu WQ, Zhang SY, Fu SQ, Fu QH, Lu WN, Zhang J, Liang ZY, Zhang Y, Liang TB Tags: J Zhejiang Univ Sci B Source Type: research