Asymmetric dimethylarginine as a potential biomarker for management and follow-up of phenylketonuria

Conclusion: In this study, we have evaluated the reliability of ADMA as a potential biomarker of adequate metabolic control and possible nutritional risk in a long-term PKU patient population.What is Known:•Although PKU individuals have lower values of ADMA even with blood Phe levels in the recommended range, little attention is payed to other metabolic pathways.What is New:•ADMA could be used as new biomarker for PKU management and follow-up of the diet, after evaluating their reliability in a long-term PKU patient population.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research