Mesothelioma Tissue Bank Identifies Survival Factors
This study was on the exploration of risk factors affecting mortality.”
The Lancet Respiratory Medicine published the findings early in 2019.
Factors Associated with Longer Survival
Age under 45 years when diagnosed
Female gender
Peritoneal mesothelioma subtype
Epithelioid histology subtype
Treatment including surgery and chemotherapy
Stage 1 at time of diagnosis
“The identification of these factors could help patients at risk for therapy failure who may benefit from novel interventions, or avoiding treatments that are not effective, or with high mortality risk,” the researchers concluded.
Median Survival Time Varies Dramatically
Based on an analysis of 888 cases, the median overall survival of the cohort was 15 months. It was 59 months for those diagnosed under the age of 45 and only 10 months for those 75 years or older.
Females had a 22-month median overall survival. Those who reported no known exposure to asbestos, regardless of sex, had a 20-month overall survival.
The site of the disease also changed survival dramatically. The average survival time of patients with peritoneal mesothelioma was 30 months, which was more than double that of pleural mesothelioma patients.
Patients with the epithelioid cell type of mesothelioma had a distinct advantage with an 18-month survival median, compared to just 10 months for the biphasic cell type and seven months for the sarcomatoid cell type.
Median overall survival rose to 23 months for th...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Daniel King Source Type: news