Inferior Quadrant of Tear Film Is More Likely to Break and Breaks Early in Patients With Dry Eyes

Purpose:
To investigate the temporal and spatial distribution of tear film breakup time via a noninvasive topographer in normal subjects and patients with dry eye disease (DED).
Methods:
A total of 77 subjects were separated into normal and DED groups based on their symptoms and tear film instabilities. In noninvasive evaluation with Oculus Keratograph, the precorneal tear film was recorded and reconstructed into a two-dimensional map that evolved with time. Whether or not each sector broke and the breakup time if it did were recorded. The map was further grouped into 4 quadrants to reveal the spatial variation.
Results:
By the end of recording, the inferior quadrant in DED subjects had a higher number of broken sectors than other quadrants (P

Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Basic Investigation Source Type: research