Percutaneous Mitral Valve Repair

Percutaneous Mitral Valve Repair Mitral regurgitation is the commonest valvular lesion, due to aging of the population at large and degenerative valvular heart disease overtaking rheumatic heart disease. Standard treatment for symptomatic severe mitral regurgitation and asymptomatic severe mitral regurgitation with left ventricular dysfunction is surgical treatment. Among surgical treatments available, mitral valve repair has lesser morbidity than replacement if the valve is amenable for repair. Surgical treatment has to be deferred very often in this elderly population with multiple comorbidities [1]. Hence the role of percutaneous mitral valve repair is catching up. Percutaneous mitral valve repair has recently found role even in functional mitral regurgitation secondary to left ventricular dysfunction and dilatation. Over the past few years, a significant clinical experience has been developed for the edge-to-edge clip technique by the MitraClip system (Abbott Laboratories, IL) for percutaneous mitral valve repair. EVEREST (Endovascular Valve Edge-to-Edge Repair Study) II study [2] was a randomized trial which compared MitraClip vs conventional surgery for degenerative mitral regurgitation. One year result of EVEREST II showed that mitral valve edge-to-edge repair was less effective than surgery for reducing mitral regurgitation, but had superior safety and similar improvements in clinical outcome. Major adverse events in percutaneous repair group was 15% while it was 48%...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: Structural Heart Disease Interventions Source Type: blogs