A Genetic Risk Score Associated with COPD Susceptibility and Lung Structure on Computed Tomography.

CONCLUSIONS: A GRS associated with COPD susceptibility was associated with CT lung structure. Lung structure may be an important mediator of heritability and determinant of personalized COPD risk. PMID: 30925230 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30925230?dopt=Abstract

Source: American Journal of Respiratory and Critical Care Medicine - March 28, 2019 Category: Respiratory Medicine Authors: Oelsner EC, Ortega VE, Smith BM, Nguyen JN, Manichaikul AW, Hoffman EA, Guo X, Taylor KD, Woodruff PG, Couper DJ, Hansel NN, Martinez FJ, Paine Iii R, Han MK, Cooper C, Dransfield MT, Criner G, Krishnan JA, Bowler R, Bleecker ER, Peters S, Rich SS, Meyers Tags: Am J Respir Crit Care Med Source Type: research