Some biochemical studies on trans fatty acid-containing diet

Publication date: Available online 29 March 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Yasmin Ali Abd El-Aal, Doaa Mohamed Abdel-Fattah, Khalifa El-Dawy AhmedAbstracttrans fatty acids (TFA's) are unsaturated fatty acid which have one or more double bond, they are present naturally and most of it is artificial, fried, baked food and margarine are major sources of TFA, there are several biological effects of TFAs on body health, various study showed that dietary TFA associated with various health disorders such as Diabetes, cardiovascular disease (CVD), Obesity, breast cancer, prostatic cancer infertility, and coronary artery disease (CAD). The World Health Organization (WHO) in 2015 encourages eliminations of trans fatty acids. The diet which related to non-communicable diseases include TFA should be eliminated, WHO's European Food and Nutrition Action Plan 2015–2020 suggested that TFAs should be less than 1% of the daily energy intake include natural origin. So the aim of this review, to know more than about trans acids, their nature, sources, and their different effect on health and how can analysis it.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research

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Publication date: 30 August 2020Source: International Journal of Pharmaceutics, Volume 586Author(s): Sujuan Zhang, Yongtai Zhang, Zhi Wang, Teng Guo, Xuefeng Hou, Zhiyuan He, Zehui He, Lina Shen, Nianping Feng
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 10 July 2020Source: Seminars in Cancer BiologyAuthor(s): Ombretta Melaiu, Valeria Lucarini, Roberto Giovannoni, Doriana Fruci, Federica Gemignani
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 10 July 2020Source: Biochimica et Biophysica Acta (BBA) - Reviews on CancerAuthor(s): Yan Zhao, Ya-Ni Zhang, Kai-Ting Wang, Lei Chen
Source: Biochimica et Biophysica Acta (BBA) Reviews on Cancer - Category: Cancer & Oncology Source Type: research
Publication date: Available online 10 July 2020Source: Biochimica et Biophysica Acta (BBA) - Reviews on CancerAuthor(s): Angana Biswas, Yetirajam Rajesh, Pralay Mitra, Mahitosh Mandal
Source: Biochimica et Biophysica Acta (BBA) Reviews on Cancer - Category: Cancer & Oncology Source Type: research
We report a 30-year-old female patient with diabetes who has acromegaloid features, prominent umbilicus, prominent muscles, prominent subcutaneous veins, and gross hepatomegaly. Near-total loss of subcutaneous fat was confirmed by whole-body magnetic resonance imaging and laboratory data revealed significant hypertriglyceridemia, uncontrolled diabetes mellitus, and heavy proteinuria with stage IIIa chronic kidney disease. Her blood film revealed thrombocytosis that on further evaluation by bone marrow biopsy was confirmed to be a myeloproliferative neoplasm (MPN); essential thrombocytosis (ET). She also had skin lesions th...
Source: Oman Medical Journal - Category: Middle East Health Tags: Oman Med J Source Type: research
We report a case of TBIRS in an Arab patient with mixed connective tissue disease (MCTD). Investigations revealed a clinical condition marked by positive anti-insulin receptor and ribonucleoprotein antibodies. The patient presented with severe hyperglycemia, weight loss, arthralgia, and acanthosis nigricans. He was managed successfully with an intensive pulsed combination regimen of cyclophosphamide and plasmapheresis augmented with high doses of prednisolone, which normalized his blood sugar levels without insulin therapy. MCTD was controlled by hydroxychloroquine. During the course of his treatment, the patient developed...
Source: Oman Medical Journal - Category: Middle East Health Tags: Oman Med J Source Type: research
Conclusions Two, Not Mutually Exclusive, Hypotheses We have reviewed and organized the literature with the intent of showing the existing parallels between excessive fat accumulation and the aging process. We have categorized these reports following what have been proposed to be the nine hallmarks of aging (21) (Figure 1). Based on the evidence, two distinct hypotheses can be proposed. One is that the cellular responses provoked by an excess of nutrients cause obesity, and that obesity is responsible for accelerating the pace of aging. Supporting this hypothesis are the observations that knocking out the fat-specific ins...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Conclusion The periconceptional environment and lifestyle factors modify sperm epigenome. This alteration might be maintained in the zygote and throughout development, thereby leading to the inheritance of newly acquired pathologies. The role of sperm miRNA, not only as innovative markers of fertility issues but also as vectors involved in the inheritance of paternal diseases, appears to be crucial. Overweight and obesity seem to alter sperm miRNA profile, thereby leading to transmission of different miRNA profiles in zygote, with consequences on embryo development. In long term, metabolic disorders have been described in...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Discussion Klinefelter syndrome (KS) is a common genetic abnormaly with a prevalence of 1 in ~650 male births. It was first described in 1942 by Dr. Harry Klinefelter. It is associated with at least one extra X chromosome with the most common karyotype (~80% of patients) being 47 XXY. Other karyotypes are seen along with mosaicism. It is believed that although it is very prevalent, only about 25-33% of people with KS are identified. About 10% are identified before puberty with the rest usually identified because of hypogonadism and tall stature especially in teenage years or due to infertility in adulthood. KS is diagnosed...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Spring is upon us, a perfect time of year for detoxification. As the seasons change, many of us are motivated to do 'spring cleaning' in our homes and gardens. The same need applies to our bodies. When the body is detoxified, it can function more efficiently and gain resilience. Physicians have been seeing increasing symptoms of toxicity in their patients over the last few decades. Hormone imbalances, obesity, mental fog, memory loss, fatigue, lack of vitality, metabolic syndrome, sleep disturbances are all manifestations of a toxic body. Conventional medicine does not acknowledge toxicity as an important health issue, but...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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