Viruses, Vol. 11, Pages 312: Discovery and Further Studies on Giant Viruses at the IHU Mediterranee Infection That Modified the Perception of the Virosphere
Viruses, Vol. 11, Pages 312: Discovery and Further Studies on Giant Viruses at the IHU Mediterranee Infection That Modified the Perception of the Virosphere
Viruses doi: 10.3390/v11040312
Authors:
Clara Rolland
Julien Andreani
Amina Louazani
Sarah Aherfi
Rania Francis
Rodrigo Rodrigues
Ludmila Silva
Dehia Sahmi
Said Mougari
Nisrine Chelkha
Meriem Bekliz
Lorena Silva
Felipe Assis
Fábio Dornas
Jacques Khalil
Isabelle Pagnier
Christelle Desnues
Anthony Levasseur
Philippe Colson
Jônatas Abrahão
Bernard Scola
The history of giant viruses began in 2003 with the identification of Acanthamoeba polyphaga mimivirus. Since then, giant viruses of amoeba enlightened an unknown part of the viral world, and every discovery and characterization of a new giant virus modifies our perception of the virosphere. This notably includes their exceptional virion sizes from 200 nm to 2 µm and their genomic complexity with length, number of genes, and functions such as translational components never seen before. Even more surprising, Mimivirus possesses a unique mobilome composed of virophages, transpovirons, and a defense system against virophages named Mimivirus virophage resistance element (MIMIVIRE). From the discovery and isolation of new giant viruses to their possible roles in humans, this review shows the active contribution of the University Hospital Institute (IHU) Mediterranee Infection to the growing knowledge of the giant viruses’ field...
Source: Viruses - Category: Virology Authors: Clara Rolland Julien Andreani Amina Louazani Sarah Aherfi Rania Francis Rodrigo Rodrigues Ludmila Silva Dehia Sahmi Said Mougari Nisrine Chelkha Meriem Bekliz Lorena Silva Felipe Assis F ábio Dornas Jacques Khalil Isabelle Pagnier Christelle Desnues Anth Tags: Review Source Type: research