First occurrence of pediatric urinary tract infections caused by Streptococcus pneumoniae in a teaching hospital in Tunisia

We report here two cases of urinary tract infections occurred in pediatrics patients with vesicoureteral reflux and renal stones. It becomes essential to consider pneumococcal UTI in the presence of clinical signs and symptoms associated co-existing predisposing factors.
Source: Reviews in Medical Microbiology - Category: Microbiology Tags: BACTERIOLOGY Source Type: research

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Authors: Imam TH, Patail H, Patail H Abstract Medullary Sponge Kidney (MSK) disease is a rare congenital malformation of the distal nephron where cystic dilatation is appreciable in the collecting ducts and renal papillae. Most cases of the malformation are thought to arise from a malfunction within neurotrophic factor and tyrosine kinase interactions. Presentation and prognosis are usually indolent; however, they include urinary tract infections (UTI), nephrolithiasis and nephrocalcinosis, distal renal tubular acidosis (dRTA) and hypocitraturia. With an insidious and asymptomatic onset, MSK is a difficult renal ma...
Source: International Journal of Nephrology and Renovascular Disease - Category: Urology & Nephrology Tags: Int J Nephrol Renovasc Dis Source Type: research
ConclusionsWe found that PH3 was significantly diagnosed in our urolithiasis patients during childhood. Nine novel HOGA1 mutations were identified in association with PH3, which provide a first-line investigation in Chinese PH3 patients. The eGFR was normal in all children with PH3. This finding is in contrast to the early impairment of renal function in PH1 and PH2.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
ConclusionsUse of antibiotics for more than 2 months in early adulthood and middle age is associated with higher risk for urinary stone disease in later life.
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
An 82-year-old male, with a history of bowel cancer with partial colectomy, gastroesophageal reflux disease, remote partial gastrectomy for peptic ulcer disease, and no documented prior kidney disease, presents with several months of fatigue and subacute decline in kidney function. He had no history of diabetes, hypertension, kidney stones, or prior urinary tract infections. He denied use of nonsteroidal anti-inflammatory agents, herbal medications, and recent antibiotics. There was no family history of renal disease.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Make Your Diagnosis Source Type: research
Purpose of review Uromodulin (UMOD), also known as Tamm–Horsfall protein, is the most abundant protein in human urine. UMOD has multiple functions such as protection against urinary tract infections and nephrolithiasis. This review outlines recent progress made in UMOD's role in renal physiology, tubular transport, and mineral metabolism. Recent findings UMOD is mostly secreted in the thick ascending limb (TAL) and to a lesser degree in the distal convoluted tubule (DCT). UMOD secretion is regulated by the calcium-sensing receptor. UMOD upregulates ion channels [e.g., renal outer medullary potassium channel, tra...
Source: Current Opinion in Nephrology and Hypertension - Category: Urology & Nephrology Tags: MOLECULAR CELL BIOLOGY AND PHYSIOLOGY OF SOLUTE TRANSPORT: Edited by Vivek Bhalla and Alan C. Pao Source Type: research
Struvite urolithiasis with bacterial urinary tract infection (UTI) is commonly reported in dogs; few data exist to describe successful dissolution protocols in dogs with naturally occurring disease. We hypothe...
Source: BMC Veterinary Research - Category: Veterinary Research Authors: Tags: Research article Source Type: research
AbstractPurposeUrinary tract infection (UTI) is a common complication after flexible ureteroscopy (fURS) despite technical precautions to avoid infectious complications. The aim was to investigate incidence and predictive risk factors of UTI following fURS procedure.Patients and methodsWe conducted a retrospective study including consecutive fURS performed in our center from January 2015 to March 2019. The indications were: nephrolithiasis management and diagnosis and conservative treatment of upper urinary tract urothelial carcinomas (UTUC). Since 2015, we had technical precautions to avoid postoperative infectious compli...
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
Abstract INTRODUCTION AND OBJECTIVES: The study was conducted to identify the risk factors of upper tract stone formation in patients with diversions after radical cystectomy (RC). MATERIALS AND METHODS: All patients with diversion after RC were collected in our center from January 2005 to December 2013. Three different common diversions were included: Orthotopic neobladder (ON: 168 patients), Ileal Conduit (IC: 93 patients) or Ureterocutaneostomy (UC: 104 patients). Univariable and multivariable logistic regression analysis were conducted to identify the independent predictors of stone formation in the upper...
Source: Actas Urologicas Espanolas - Category: Urology & Nephrology Authors: Tags: Actas Urol Esp Source Type: research
Case report describes management of a 25-year-old male with nephrolithiasis who developed colistin neurotoxicity. Negative urine culture for Pseudomonas aeruginosa was achieved on 5th day of treatment with meropenem 6  g/day, gentamicin 2 mg/kg and rifampicin 300 mg
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
An infection involving the kidney is known as acute pyelonephritis. This usually starts as a urinary tract infection that moves to the kidney. Acute pyelonephritis is commonly treated with antibiotics. Imaging studies are not usually required but may be needed if an individual has a history of diabetes or prior history of kidney stones, is immunocompromised, or is not responding to treatment.
Source: Journal of the American College of Radiology : JACR - Category: Radiology Authors: Tags: Appropriate use criteria Source Type: research
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