Efficacy of venlafaxine extended release in major depressive disorder patients: effect of baseline anxiety symptom severity

Effects of baseline anxiety on the efficacy of venlafaxine extended release versus placebo were examined in a post hoc pooled subgroup analysis of 1573 patients enrolled in eight short-term studies of major depressive disorder. Anxiety subgroups were defined based on baseline 17-item Hamilton Rating Scale for Depression Item 10 score
Source: International Clinical Psychopharmacology - Category: Psychiatry Tags: Original Articles Source Type: research

Related Links:

For anyone interested: https://psyarxiv.com/bhyg9/ Apparently, BA does not beat out active control. I am sure the common factors folks will love this. However, I caution that camp not to conflate studies of depression and anxiety with more severe problems.
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Psychology [Psy.D. / Ph.D.] Source Type: forums
This study explored the dynamic relationship between social physique anxiety and depressive symptoms in a sample of young adults over a six-month period. Using a two-wave longitudinal design, data were collected from a sample of 398 undergraduate students (47.70% females, 97.50% white) aged between 18 and 30 years old (M = 20.47, SD = 2.42). Results from the latent change score model showed that initial levels of social physique anxiety significantly predicted changes in depressive symptoms (β = 0.35, p = .002). Conversely, initial levels of depressive symptoms did not significantly predict changes i...
Source: Journal of Applied Developmental Psychology - Category: Child Development Source Type: research
Due to early onset and rising prevalence rates, there is an established need for early identification of youth demonstrating symptoms of internalizing disorders (e.g., anxiety and depression). Accordingly, calls have been made for the use of universal scre...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Objective: Latinx young adults in college (ages 18-25  years) are at a heightened risk for health disparities and there is a need to understand individual-based characteristics that are related to such health inequalities including anxiety, depress...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
CONCLUSION: Screening for anxiety is recommended even during the acute phase of stroke, considering its independent detrimental effect on functional prognosis. Screening for anxiety during the chronic phase is also encouraged, as this may reflect the functional status of stroke. PMID: 31698556 [PubMed - as supplied by publisher]
Source: Psychiatry Investigation - Category: Psychiatry Tags: Psychiatry Investig Source Type: research
Conclusion: KY shows promise as an add-on option for OCD patients unresponsive to first line therapies. Future studies will establish KY’s relative efficacy compared to Exposure and Response Prevention and/or medications, and the most effective treatment schedule.Clinical Trial Registration:www.ClinicalTrials.gov, identifier NCT01833442.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
imer Davies Nature-based health interventions (NBIs) for the treatment of poor mental health are becoming increasingly common, yet evidence to support their effectiveness is lacking. We conduct a pilot study of a six-week intervention, aiming to engage individuals with wetland nature for the treatment of anxiety and/or depression. We employed a mixed methods design, using questionnaires, focus groups and semi-structured interviews to evaluate the intervention from the perspective of participants (n = 16) and healthcare professionals (n = 2). Results demonstrate significant improvements in mental health across a rang...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
The objective of this research was to examine the pathway from public stigma, to perceived stigma, to depression in adolescents via internalized stigma. Adolescents in grade 7 through 9 from a junior high school in Changhua County in Taiwan completed self-administered surveys from March to July in 2018. Adolescents were asked questions regarding depressive symptoms, obesity-related perceived stigma, and internalized stigma. Structural equation modeling was used to fit the pathway model. The pathway was first analyzed with the full sample and then stratified by actual and perceived weight status. Our final analytic sample c...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
AbstractLittle is known about the role of mindfulness and self-compassion in obsessive-compulsive disorder. This cross-sectional study examined associations of mindfulness and self-compassion with obsessive-compulsive disorder symptoms and with the obsessive beliefs and low distress tolerance thought to maintain them. Samples of treatment-seeking adults (N  =  1871) and non-treatment-seeking adults (N  =  540) completed mindfulness, self-compassion, obsessive-compulsive disorder, anxiety, depression, obsessive beliefs and distress tolerance questionnaires. Participants with clinically significan...
Source: Cognitive Therapy and Research - Category: Psychiatry & Psychology Source Type: research
ConclusionsResults indicate a clearer benefit among students, yet also point to the supportive role mindfulness can assume among teachers. Systemic and implementation factors significantly shaped course results and experience in both populations.
Source: Mindfulness - Category: Psychiatry & Psychology Source Type: research
More News: Anxiety | Depression | Effexor | Psychiatry | Study