A Case of Metastatic Prostate Cancer to the Urethra that Resolved after Androgen Deprivation Therapy

An 83 year-old male with Gleason score 4+3 prostatic adenocarcinoma status post brachytherapy developed obstructive voiding symptoms nine years after brachytherapy. PSA was 0.67. Cystoscopy noted multiple papillary urethral tumors concerning for primary urethral carcinoma. Immunophenotype of biopsies supported diagnosis of Gleason score 4+4 prostatic adenocarcinoma. Androgen deprivation therapy was started. Cystoscopy performed four years later, for microhematuria workup, noted complete resolution of the urethral tumors.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research