Why the wheelchair? Could it be gout?

When Paul Manafort appeared in court for sentencing recently, he was in a wheelchair and pleaded for leniency, in part because “his confinement had taken a toll on his physical and mental health.” He reportedly had symptoms of depression and anxiety — but what was the health problem that put him in a wheelchair? According to multiple news reports, the answer is gout. Yes, that ancient disease you may have thought didn’t exist anymore has stricken Mr. Manafort. He joins the rising number of people in the country diagnosed with this common disease. What is gout? Gout is a cause of severe joint pain and inflammation. This form of arthritis develops when crystals of uric acid (a normal byproduct of our body’s metabolism) deposit near joints and other parts of the body. Gout develops because the body makes too much uric acid, the kidneys don’t get rid of enough of it, or a combination of both. For some, dietary factors — consuming foods and beverages that produce a lot of uric acid — seem to play an important role. For others, the problem may be one or more medications that cause the level of uric acid to rise. Genetic factors are also important; the way the body handles uric acid may vary based on the genes you inherit. The observation that gout sometimes runs in families supports a genetic contribution. Some facts about gout Gout is on the rise. According to the most recent estimates, nearly 4% of the adult population in US no...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Arthritis Bones and joints Health Inflammation Source Type: blogs

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Publication date: February 2020Source: Journal of Catalysis, Volume 382Author(s): Nirala Singh, Udishnu Sanyal, Griffin Ruehl, Kelsey A. Stoerzinger, Oliver Y. Gutiérrez, Donald M. Camaioni, John L. Fulton, Johannes A. Lercher, Charles T. CampbellAbstractThe mechanisms of aqueous-phase thermal catalytic hydrogenation (TCH) and electrocatalytic hydrogenation (ECH) of organic molecules over Pt group metals are not as well-understood as gas-phase thermal catalytic hydrogenation. In gas-phase, the reactions generally occur via a Langmuir-Hinshelwood mechanism with adsorbed hydrogen adding to adsorbed organics. Here, we ...
Source: Journal of Catalysis - Category: Chemistry Source Type: research
BACKGROUND: Suicide is the third leading cause of death worldwide among youth aged 10- to 19, and mental disorders are often associated in the etiology of suicidal behavior. Mental disorders are often under-diagnosed and under-treated in young people, a si...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
BACKGROUND: Suicide prevention remains challenging among youth, as many do not disclose suicidal ideation. Nearly one-third of American Indian and Alaska Native (AI and AN, tribal, or native) youth see concerning messages on social media at least weekly. ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Young Adults Source Type: news
As the prevalence of type 1 and type 2 diabetes increases and population-level patterns of alcohol and illicit drug use evolve, clinicians will continue to encounter people with diabetes whose substance use is affecting health outcomes. Substance use contr...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Authors: Ertel KA, Hallam JE, Hillman AR Abstract BACKGROUND: Individuals participating in exercise beyond their level of fitness may be at higher risk for exercise-induced muscle damage, however the impact of training status on muscle damage development is not well understood. The purpose of this study was to measure skeletal muscle damage and soreness after five days of high and low intensity exercise in previously trained and untrained individuals. METHODS: Eighteen males and females (9 trained and 9 untrained) completed five consecutive days of high intensity (HI) exercise and five consecutive days of low i...
Source: Journal of Sports Medicine and Physical Fitness - Category: Sports Medicine Tags: J Sports Med Phys Fitness Source Type: research
Authors: Qadir KJ, Zangana KO Abstract BACKGROUND: Regular physical activity and exercise is the third management for the child with diabetes mellitus after diet regime and insulin therapy. The aim of the study is to evaluate the effect of swimming on glycemic control for a male adolescent with type 1 diabetes mellitus. OBJECTIVE: The study evaluates the effect of swimming on glycemic control for a male adolescent with type 1 diabetes mellitus. METHODS: The quasi-experimental design was conducted on 40 male adolescents with typ1 diabetes, then divided into two groups; study and control groups. 20 adolescent...
Source: Journal of Sports Medicine and Physical Fitness - Category: Sports Medicine Tags: J Sports Med Phys Fitness Source Type: research
Suprarenal abdominal aortic coarctation (SAAC) is a congenital midaortic syndrome that develops owing to a developmental anomaly in the fusion of the embryonic dorsal aortae. This condition is associated with severe hypertension, which is usually the indication for intervention. Open surgery is the primary treatment and it typically involves thoracoaortic bypass (TAB), and less commonly patch aortoplasty (PA). Bypass to the visceral vessels has also been performed in conjunction with TAB or PA. The majority undergoing intervention for SAAC are children and adolescents; therefore, the benefits of surgical intervention must ...
Source: Journal of Vascular Surgery - Category: Surgery Authors: Tags: Invited commentary Source Type: research
Authors: BaHammam AS, Almeneessier AS Abstract Previous studies have assessed the role of gender and menopause in Obstructive Sleep Apnea (OSA). It is well known that menopause is a major risk factor for OSA. However, analogous studies on obesity Hypoventilation Syndrome (OHS) are limited. Recent studies have suggested that OHS is more prevalent in postmenopausal women. Moreover, women with OHS seem to have excess comorbidities, including hypothyroidism, hypertension, pulmonary hypertension, and diabetes mellitus, compared to men. In the present perspective, we discuss recent data on the prevalence and comorbiditie...
Source: Open Respiratory Medicine Journal - Category: Respiratory Medicine Tags: Open Respir Med J Source Type: research
75 years old patient, with controlled diabetes and hypertension, very fit. he underwent in 2009, a radical prostatectomy followed 30 fractions of adjuvant 3D conformal radiation therapy to the prostatic bed only. in 2018: PSA rise to 2.16 2019: PSA 2.16 Pet PSMA showed a 7 mm LN at the level of L4-5 secondary lesion, with no recurrence in the tumor bed, neither in bone or other LNs. He was put on decapeptyl + casodex. please vote the poll
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Radiation Oncology Source Type: forums
I haven't used Stimwave since fellowship. Anyone using their technology for peripheral nerve stim? Results? Pros/Cons and feedback from patients? If I were going to use it, it would probably be for suprascapular neuralgia, genicular nerualgia, and/or SI joint pain vs cluneal neuralgia, when other options have failed (i.e. RF).
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
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