Cancers, Vol. 11, Pages 446: Ion Channel Expression in Human Melanoma Samples: In Silico Identification and Experimental Validation of Molecular Targets

In conclusion, the present study identified five ion channels that can potentially serve as sensitive and specific markers in human melanoma specimens and demonstrates that the antifungal drug miconazole, known to target one of the five identified ion channels, exerts strong and specific anti-melanoma effects in vitro.

Source: Cancers - March 28, 2019 Category: Cancer & Oncology Authors: Daniela D ’Arcangelo Francesca Scatozza Claudia Giampietri Paolo Marchetti Francesco Facchiano Antonio Facchiano Tags: Article Source Type: research