Epidemiologic Trends and Clinical Features of Pneumocystis jirovecii Pneumonia in Non-HIV Patients in a Tertiary-Care Hospital in Korea over a 15-Year-Period.
Epidemiologic Trends and Clinical Features of Pneumocystis jirovecii Pneumonia in Non-HIV Patients in a Tertiary-Care Hospital in Korea over a 15-Year-Period. Jpn J Infect Dis. 2019 Mar 26;: Authors: Lee HY, Choi SH, Kim T, Chang J, Kim SH, Lee SO, Kim MN, Sung H Abstract Subsequent to the increasing use of immunosuppressant therapy, Pneumocystis jirovecii pneumonia (PcP) has emerged as a life-threatening condition in human immunodeficiency virus (HIV)-negative patients. We investigated changes in epidemiological and clinical characteristics among PcP cases with and without HIV infections. Data of 424 patients diagnosed with PcP in a 2,700-bed Korean tertiary care hospital between February 2003 and April 2017 were retrospectively analyzed. The study included patients with compatible clinical findings in whom PcP was confirmed via direct immunofluorescence assay. The annual average number of cases increased from 12.2 (initial 5-year period) to 42.2 (recent 5-year period). In HIV-negative patients, hematologic malignancy (34.8%) and solid organ transplantation (32.9%) were the most frequent major underlying conditions, and immunosuppressive therapies including corticosteroids (342/362; 94.5%) and chemotherapy (122/362; 33.7%) were significantly associated with PcP infection (p
A recap of Tuesday’s top stories: Pneumonia number one killer of children; Australia’s wildfires rage on; Ebola vaccine gets green light; new child labour and trafficking study; Malnutrition soars in Latin America and Caribbean; Intellectual Property chief encourages innovation.
In conclusion, we emphasize that it is of importance to work closely with the hospital administration to take measures and that necessary assistance is provided. PMID: 31709934 [PubMed - in process]
CONCLUSION: This study identified prior antibiotic exposure, recent surgery and the use of invasive procedures as significant risk factors for colonization or infection with CRE. Also, the need for public awareness, continuing education for healthcare professionals, optimum use of invasive devices, enhanced surveillance, and antimicrobial stewardship are highlighted here which can limit CRE transmission in healthcare facilities. PMID: 31707406 [PubMed - in process]
Pneumonia, an entirely preventable disease, kills more children than any other illness in the world, one child every 39 seconds. But although that statistic is well known, funding to improve survival rates continues to come up short, the UN and partners warned on Tuesday, World Pneumonia Day.
By Alice Rwema Iribagiza, Communications Officer, Ingobyi Nurse Esther at work. Photo credit: IntraHealth International.November 12, 2019Esther Mukahabiyambere is one of 326 district-based mentors trained on the Integrated Management of Childhood Illness (IMCI) approach. Through the USAID-fundedIngobyi Activity, health workers are using IMCI in Rwanda to prevent and treat pneumonia, diarrhea, malnutrition, and malaria. The project equips health care providers with clinical knowledge, skills, and attitudes to improve the quality of care, helping the government of Rwanda reduce child mortality, particularly the managemen...
[Daily Trust] The death of 162,000 Nigerian children, of pneumonia in 2018, is the highest of the estimated total of 802,000 pneumonia deaths globally, the Save the Children said this in Abuja.
[This Day] Abuja -A leading child rights organisation, Save the Children, has revealed that pneumonia claimed the lives of 162,000 children below the age of five in Nigeria in 2018.
[Vanguard] A new report by the United Nations Children Fund (UNICEF) shows Nigeria recorded the highest global deaths from pneumonia at 162,000 last year.
(Murdoch Childrens Research Institute) A new study has found severe pneumonia decreases by 35 per cent in children who receive a vaccine against a pneumonia-causing bacteria.
Emergency admissions have risen more than 50 per cent over the last decade, with 56,000 British children hospitalised with the condition last year.