Differential Action of TGR5 Agonists on GLP-2 Secretion and Promotion of Intestinal Adaptation in Piglet Short Bowel Model.

In conclusion, UA is an effective oral GLP-2 secretagogue in parenterally-fed pigs but was not capable of augmenting GLP-2 secretion nor the intestinal adaptation response after massive small bowel resection.
PMID: 30920308 [PubMed - as supplied by publisher]

Source: Am J Physiol Gastroi... - March 27, 2019 Category: Gastroenterology Authors: Lin S, Stoll B, Robinson J, Pastor JJ, Marini JC, Ipharraguerre IR, Hartmann B, Holst JJ, Cruz SM, Lau PE, Olutoye OO, Fang Z, Burrin DG Tags: Am J Physiol Gastrointest Liver Physiol Source Type: research