Pacing in proximity to scar during cardiac resynchronization therapy increases local dispersion of repolarization and susceptibility to ventricular arrhythmogenesis.

Cardiac resynchronization therapy (CRT) increases the risk of ventricular tachycardia (VT) in patients with ischemic cardiomyopathy (ICM) when the left ventricular (LV) epicardial lead is implanted in proximity to scar.

Source: Heart Rhythm - March 27, 2019 Category: Cardiology Authors: Caroline Mendonca Costa, Aurel Neic, Eric Kerfoot, Bradley Porter, Benjamin Sieniewicz, Justin Gould, Baldeep Sidhu, Zhong Chen, Gernot Plank, Christopher A. Rinaldi, Martin J. Bishop, Steven A. Niederer Source Type: research