Sceletorines A and B, two minor novel dimeric alkaloids of Mesembryanthemum tortuosum (synonym Sceletium tortuosum)

Publication date: June 2019Source: Phytochemistry Letters, Volume 31Author(s): Hongquan Yin, Zulfiqar Ali, Yuanqing Ding, Yan-Hong Wang, Michael. J. Cunningham, Mohamed A. Ibrahim, Amar G. Chittiboyina, Wei Wang, Alvaro M. Viljoen, Ikhlas A. KhanAbstractSceletorines A and B, two unique alkaloids, were isolated for the first time from the aerial parts of Mesembryanthemum tortuosum. Their structures were determined by the extensive spectroscopic methods and their absolute configuration was established with ECD calculations. Plausible biosynthetic pathways for 1 and 2 are proposed and a relationship to the previously assumed artifact, channaine is also addressed.Graphical abstract

Source: Phytochemistry Letters - March 28, 2019 Category: Chemistry Source Type: research