Antibiotic use practice and predictors of hospital outcome among patients with systemic bacterial infection: Identifying targets for antibiotic and health care resource stewardship.

Malpractice and excess use of antimicrobials have been associated with multiple costs, including the development of resistant bacteria, which has become a threat to the human health. The aim of this study, therefore, was to assess the antibiotic use practice and to identify predictors of hospital outcome to uncover targets for stewardship. Generally, this observation entails an appropriate infection management and antimicrobial use policy. Any future policy should better start by addressing cases like pneumonia, and sepsis and drugs like cephalosporins.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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A blood test can identify a subgroup of pneumonia patients at increased risk for developing acute respiratory failure or sepsis, according to new research.Reuters Health Information
Source: Medscape Emergency Medicine Headlines - Category: Emergency Medicine Tags: Pulmonary Medicine News Source Type: news
We reported a case of bronchopulmonary lophomoniasis in a Malaysian female with systemic lupus erythromatosus. She presented with productive cough, shortness of breath and high-grade fever for 2 weeks. Physical examination revealed bronchial sound and crackles over the left lung with, reduced expansion and dull percussion in lower left lobe. Chest radiography showed consolidation of the left lung. Routine laboratory tests revealed general low cell count. Blood and sputum culture were negative. Bronchoalveolar lavage stain and culture for bacterial and fungal were negative. Bronchoalveolar lavage for Lophomonas blattarum wa...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Publication date: December 2019Source: Microbial Pathogenesis, Volume 137Author(s): Seok Hyeon Na, Man Hwan Oh, Hyejin Jeon, Yun-Ki Lee, Byungheon Lee, Minsang Shin, Je Chul LeeAbstractBioluminescence imaging is a non-invasive tool for in vivo real-time monitoring of infectious disease progression in animal models. However, no bioluminescence imaging assay has been developed to monitor Acinetobacter baumannii infections. In the current study, bioluminescent strains of A. baumannii ATCC 17978 and its isogenic ΔompA mutant were constructed by integrating the promoter of the ompA gene and the luxCDABE luciferase gene in...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
This report describes a case of septicaemia triggered by SI. The patient was a 40 year-old woman, who was diagnosed with Cornelia de Lange syndrome (CdLS). She was hospitalized in a medical long-term care sanatorium and was recently transferred from a familiar sanatorium. She started to bite herself on the mandibular labial alveolar mucosa; this had never been observed. As the self-biting wound gradually increased and the resultant inflammation spread to surrounding tissues, she was referred to our hospital. During the course of treatment, she suffered from septicaemia secondary to aspiration pneumonia. When a case of SI...
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - Category: ENT & OMF Source Type: research
Conclusion: Laparoendoscopic single-site surgery may be a feasible and safe technique for staging early-stage ovarian/tubal cancer. This approach has some advantages included providing easier access to the upper abdominal regions when performing high-level infrarenal para-aortic lymphadenectomy; the 2-cm elastic incision favors fast specimen extraction and colpotomy are avoided. However, the long-term oncologic outcomes need to be further investigated. PMID: 31595144 [PubMed - in process]
Source: JSLS : Journal of the Society of Laparoendoscopic Surgeons - Category: Surgery Tags: JSLS Source Type: research
Increasing number of hospitalized children with community acquired pneumonia (CAP) is co-detected with Mycoplasma pneumoniae (Mp). The clinical characteristics and impact of Mp co-detected with other bacterial an...
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Tags: Research article Source Type: research
Publication date: October 2019Source: Annals of Emergency Medicine, Volume 74, Issue 4, SupplementAuthor(s): M.L. Oliveira, G.L. Marina, B.D. Frediani, B. Hermes, A.J. Cesar, R.S. Correa, B.R. Antonio, M.J. Flavio, S.H. Possolo
Source: Annals of Emergency Medicine - Category: Emergency Medicine Source Type: research
AbstractNivolumab is an anti-programmed cell death-1 antibody that is utilized as an immune checkpoint inhibitor for several malignancies. However, this agent is associated with immune-related adverse events (irAEs), mainly in the spectrum of autoimmune disease including interstitial pneumonia, colitis, type 1 diabetes, and renal impairment. We herein present the case of a 59-year-old man with renal cell carcinoma who developed worsening renal function approximately 4  months after initiation of nivolumab. Urinalysis showed proteinuria and microscopic hematuria along with increase levels ofN-acetyl- β-d-glucosami...
Source: CEN Case Reports - Category: Urology & Nephrology Source Type: research
AbstractBackgroundExploratory laparotomy (EL) has been the definitive diagnostic and therapeutic modality for operative abdominal trauma in the US. Recently, many trauma centers have started using diagnostic laparoscopy (DL) in stable trauma patients in an effort to reduce the incidence of non-therapeutic laparotomy (NL). We aim to evaluate the incidence of NL in the trauma population in the US and compare the outcomes between DL and NL.MethodsUsing ICD-9 codes, the National Trauma Data Bank (2010 –2015) was queried for patients undergoing any abdominal surgical intervention. Patients were divided into two groups: di...
Source: Surgical Endoscopy - Category: Surgery Source Type: research
ConclusionSince false positive PCR results were obtained, perhaps due to colonization, we suggest that the diagnosis of PCP should be based on a combination of clinical symptoms, underlying diseases, and PCR results.
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research
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