ABCB1 2677G > T single nucleotide polymorphism influences warfarin dose requirement for warfarin maintenance therapy.

ABCB1 2677G>T single nucleotide polymorphism influences warfarin dose requirement for warfarin maintenance therapy. Br J Biomed Sci. 2019 Mar 25; Authors: Gopisankar MG, Hemachandren M, Surendiran A Abstract This work represents an advance in biomedical science because it shows, in a singlecentre study of 210 patients, an association between ABCB1 2677 G>T genetic polymorphism and the maintenance dose requirement of warfarin for patients who have achieved a stable INR. Hence incorporation of this polymorphism to algorithms for dose prediction of warfarin may improve the accuracy of dose prediction. PMID: 30907254 [PubMed - as supplied by publisher]
Source: British Journal of Biomedical Science - Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research