Increasing Prevalence of Orthostatic Hypotension as a Cause of Syncope With Advancing Age and Multimorbidity

During recent years, syncope studies have included an increasing  number of older subjects with multimorbidity.1–4 Moreover, increasing awareness of pathophysiology today allows a more accurate differential diagnosis of this condition.5 Yet how syncope etiology changes with advancing age and increasing multimorbidity is still unclear. The present paper thus ai med at comparing and discussing the results of 3 multicentre studies, and analysing how syncope etiology changes with age and the presence of chronic conditions, with a specific focus on dementia.
Source: Journal of the American Medical Directors Association - Category: Health Management Authors: Tags: Editorial Source Type: research

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DiscussionOur findings raise the possibility that APOE ε4 carrier status may modify the relationship between postoperative day 2 CRP levels and postoperative delirium.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
Publication date: Available online 20 November 2019Source: Alzheimer's &DementiaAuthor(s): Hector M. González, Wassim Tarraf, Myriam Fornage, Kevin A. González, Albert Chai, Marston Youngblood, Maria de los Angeles Abreu, Donglin Zeng, Sonia Thomas, Gregory A. Talavera, Linda C. Gallo, Robert Kaplan, Martha L. Daviglus, Neil SchneidermanAbstractHispanics/Latinos are the largest ethnic/racial group in the United States and at high risk for Alzheimer's disease and related dementia (ADRD). Yet, ADRD among diverse Latinos is poorly understood and disparately understudied or unstudied compared to other ethnic/...
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
DiscussionEarly “subtle cognitive decline” among Aβ+ CN on a sensitive cognitive composite demonstrably increases risk for imminent clinical disease progression and functional impairment.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
Publication date: Available online 20 November 2019Source: NeuronAuthor(s): Fares Bassil, Hannah J. Brown, Shankar Pattabhiraman, Joe E. Iwasyk, Chantal M. Maghames, Emily S. Meymand, Timothy O. Cox, Dawn M. Riddle, Bin Zhang, John Q. Trojanowski, Virginia M.-Y. LeeSummaryStudies have shown an overlap of Aβ plaques, tau tangles, and α-synuclein (α-syn) pathologies in the brains of Alzheimer’s disease (AD) and Parkinson’s disease (PD) with dementia (PDD) patients, with increased pathological burden correlating with severity of cognitive and motor symptoms. Despite the observed co-pathology and c...
Source: Neuron - Category: Neuroscience Source Type: research
  Look at Kimberly’s dramatic transformation in appearance after just two months on the Wheat Belly lifestyle: the lateral dimensions of her face are reduced, her cheeks are no longer bloated, the around-the-eye swelling is gone and her eyes are bigger. She lost “only” 20 pounds but, judging by the “deflation” of her facial features, it looks more like 100 pounds—this is what happens when you reverse the body-wide inflammation caused by wheat/grain consumption. “I didn’t recognize myself! This side-by-side spoke volumes! I’ve lost about 20 pounds so far. I was...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Open Inflammation Weight Loss wheat belly Source Type: blogs
Conclusions: The findings support Be EPIC's feasibility and highlight the need to address structural barriers from employers and government to ensure the delivery of person-centered dementia care.Clinical Implications: The findings highlight the need for and positive impact of person-centered communication training on home care workers, especially the value of learning by doing, reflective practice, and peer support. PMID: 31739767 [PubMed - as supplied by publisher]
Source: Clinical Gerontologist - Category: Geriatrics Tags: Clin Gerontol Source Type: research
Publication date: Available online 20 November 2019Source: Toxicology ReportsAuthor(s): Kader Cetin Cakmak, ─░lhami GülçinAbstractUsnic acid, as active dibenzofuran derivative, isolated and characterized from some lichen species. The aim of manuscript was to evaluate antioxidant, anticholinergic and antidiabetic potentials of usnic acid as an important natural product. Antioxidant profile of usnic acid determined by eight distinguishes bioanalytical antioxidant methods. The antioxidative properties of usnic acid were performed using by several bioanalytical assays. 1,1-diphenyl-2-picrylhydrazyl (DPPH·), ...
Source: Toxicology Reports - Category: Toxicology Source Type: research
BACKGROUND: Older people with cognitive impairment are at increased risk of falls; however, fall prevention strategies have limited success in this population. The aim of this paper is to review the literature to inform a theoretical framework for fall pre...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
No abstract available
Source: Neurology Today - Category: Neurology Tags: For Your Patients Source Type: research
CONCLUSIONS: Common comorbidities modify the association of frailty with postoperative survival; however, this effect was only apparent when analyses accounted for effect modification on the absolute risk difference, as opposed to relative scale. While the relative scale is more commonly used in biomedical research, smaller effects may be easier to detect on the risk difference scale. The concurrent presence of dementia, COPD, and HF with frailty were all associated with excess mortality on the absolute risk difference scale. PMID: 31743191 [PubMed - in process]
Source: Anesthesia and Analgesia - Category: Anesthesiology Authors: Tags: Anesth Analg Source Type: research
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