Physical inactivity and vitamin D deficiency in hospitalized elderlies

This study included newly hospitalized patients aged 65  years or over at Ohchi hospital April to August in 2015. At the time of admission, serum 25(OH)D concentration was measured, and ADL, instrumental ADL (IADL), cognitive function, blood test, nursing care certification were investigated as background factors. Among 209 patients, 25(OH)D was suffici ent (>  30 ng/mL) only 14 cases (7%), insufficient (20–30 ng/mL) in 43 cases (20%), and deficient (<  20 ng/mL) in 152 cases (73%). Multivariate analysis showed that low ADL (OR 0.99, 95% CI 0.97–0.99) and low IADL (OR 0.88, 95% CI 0.78–0.99) were independent predictors of 25(OH)D deficiency in two models incorporating ADL and IADL, respectively. Furthermore, low 25(OH)D level was significan tly associated with low ADL (OR 0.95, 95% CI 0.91–0.99) and low IADL (OR 0.93, 95% CI 0.88–0.97) scores, suggesting that vitamin D deficiency may affect physical activities. Most hospitalized elderly patients in Japan were deficient for vitamin D. In addition, physical inactivity is strongly ass ociated with vitamin D deficiency.
Source: Journal of Bone and Mineral Metabolism - Category: Orthopaedics Source Type: research