Topical calcineurin inhibitors in the treatment of oral lichen planus: a systematic review and meta-analysis.

CONCLUSIONS: The evidence for tacrolimus (n=12), pimecrolimus (n=3) and cyclosporine (n=6) demonstrated that TCI may be alternative approaches when OLP does not respond to the standard protocols. Tacrolimus 0.1% should be the first drug of choice in TCI for the short-term treatment in recalcitrant OLP. Further well-designed trials are warranted to evaluate the long-term efficacy and safety of TCI. This article is protected by copyright. All rights reserved.
PMID: 30903622 [PubMed - as supplied by publisher]

Source: The British Journal of Dermatology - March 21, 2019 Category: Dermatology Authors: Sun SL, Liu JJ, Zhong B, Wang JK, Jin X, Xu H, Yin FY, Liu TN, Chen QM, Zeng X Tags: Br J Dermatol Source Type: research