Correlations between experimental myopia models and human pathologic myopia

Conclusion: The LRP2 knockout mice, retinopathy globe enlarged (rge) chicks, and normal lid-sutured chicks exhibit features typical for myopic maculopathy in patients and could serve to further elucidate the pathogenesis of myopic maculopathy.
Source: RETINA - Category: Opthalmology Tags: Review Source Type: research

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Conclusion: This self-control study without much interference factors shows that the decentration of OK lens can delay the development of myopia more effectively than being centric when uncorrected visual acuity was acceptable without obvious corneal complications, glare, or ghosting. PMID: 31827908 [PubMed]
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
Conclusions: This is probably the first case report with a novel mutation from Russia associated with CSNB1A. PMID: 31826698 [PubMed - as supplied by publisher]
Source: Ophthalmic Genetics - Category: Opthalmology Tags: Ophthalmic Genet Source Type: research
In most cases, myopia occurs due to excessive axial elongation of the eyeball. Nowadays, it is possible to correct vision even in cases of high myopia using various types of spectacles, contact lenses (CL) or refractive surgery. However, a significant concern related to myopia is the increased risk of ocular pathologies related to excessive eye growth, such as glaucoma, cataract, idiopathic retinal detachment or choroidal neovascularization [1]. In recent decades, the prevalence of myopia has increased dramatically worldwide [2 –4].
Source: Contact Lens and Anterior Eye - Category: Opthalmology Authors: Source Type: research
Condition:   Myopia Interventions:   Device: somofilcon A;   Device: etafilcon A Sponsor:   Coopervision, Inc. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
To investigate the adaptability and acceptance of a novel spectacle lens design that was recently reported to achieve a significant anti-myopia effect.
Source: American Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Original Articles Source Type: research
CONCLUSIONS Silicone oil endotamponade in PPV was associated with an increased risk of IOP at 24-month follow-up. PMID: 31811816 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Authors: Charng J, Sanfilippo PG, Lingham G, Stevenson LJ, Mackey DA, Yazar S Abstract Purpose: To consider the effect of including past sun exposure in estimating heritability and familial correlation of myopia-related traits.Methods: We calculate familial correlation and heritability of anterior chamber depth (ACD), axial length (AL), corneal curvature (CC), and spherical equivalent (SphE), with or without past sun exposure as a covariate, in a large number of unrelated nuclear families from the Raine Study (parents: Gen1, offspring: Gen2) residing in Perth, Australia, a city with a high amount of daily sunlight....
Source: Ophthalmic Genetics - Category: Opthalmology Tags: Ophthalmic Genet Source Type: research
Condition:   Myopia Intervention:   Device: Paragon CRT®100 Contact Lens Sponsors:   Paragon Vision Sciences;   TigerMed Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Journal of Ocular Pharmacology and Therapeutics, Ahead of Print.
Source: Journal of Ocular Pharmacology and Therapeutics - Category: Opthalmology Authors: Source Type: research
Myopia is the most common form of ametropia and one of the leading causes of vision impairment in the world [1]. Estimates show that in the early 21st century, myopia affected almost 30 % of the world ’s population [2]. This trend is projected to increase significantly, affecting nearly 50 % of the world’s population by 2050 [3].
Source: Contact Lens and Anterior Eye - Category: Opthalmology Authors: Source Type: research
More News: Angiography | Myopia (short sighted) | Ophthalmoscopy | Opthalmology | PET Scan