Liver Transplant Cures Rare HEHE Liver Tumor

Treatment TermsLiver transplant Overview Teresa Cumbie ’s liver cancer was so rare that her Myrtle Beach, SC oncologist had never seen anything like it. After her biopsy samples were sent for medical opinions around the country, she was diagnosed with hepatic epithelioid hemangioendothelioma (HEHE). Armed with that knowledge, Teresa started looking fo r doctors experienced with her condition. She found them at Duke University Hospital in Durham. Today, thanks to a successful liver transplant, she’s cancer-free. Hero Image2019_teresacumbie_1932x862.jpg Preview Image Content Blocks CTA Header Learn More CTA ButtonLiver Transplantation at Duke Patient Name Teresa Cumbie Patient Photo Gender Female Featured Doctors Richard F. Riedel, MD Debra L. Sudan, MD Date UpdatedMonday, March 25, 2019 Featured Doctors - Custom Specialties Medical Oncologist Transplant Surgeon BodyDisplay in Announcement Section:  Archived Medically Reviewed DateMonday, March 25, 2019 Reviewer Debra Sudan, MDThumbnail Image: Pin to Top of WiFi Page: 
Source: dukehealth.org: Duke Health News - Category: Consumer Health News Authors: Source Type: news

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Source: Diagnostic Pathology - Category: Pathology Authors: Tags: Research Source Type: research
Conclusions: Overall, patients with IHHE do well, a significant percentage of whom do not require drug therapy, particularly for those with small focal lesions. In patients with multifocal/diffuse disease, there is a high incidence of low T3 and T4 and while some of these patients did well without additional therapy, those with rapidly progressive lesions during treatment may do poorly.
Source: Journal of Pediatric Hematology Oncology - Category: Hematology Tags: Original Articles Source Type: research
ConclusionsResection or liver transplantation is worth considering for treatment of patients with HEH.
Source: Hepatobiliary and Pancreatic Diseases International - Category: Gastroenterology Source Type: research
Pseudomyogenic hemangioendothelioma (PMHE) is a rare endothelial neoplasm that involves the bones in only 14% of all cases. The optimal treatment strategy has not been established. We herein report a case of p...
Source: BMC Cancer - Category: Cancer & Oncology Authors: Tags: Case report Source Type: research
Conclusion: Malignant chondroid syringoma is genetically related to tumors with PHF1 rearrangements such as low-grade endometrial sarcoma and ossifying fibromyxoid tumor, but also with tumors having TFE3 rearrangements such as renal cell carcinoma, alveolar soft part sarcoma, PEComa, and epithelioid hemangioendothelioma. Further investigations on malignant chondroid syringomas are needed in order to determine whether genetic heterogeneity exists among them and the clinical impact of the PHF1-TFE3 fusion.
Source: Cancer Genomics and Proteomics - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
We report a case of a radically resected mediastinal EHE originating from the superior vena cava. A 79-year-old woman was referred to our hospital for colon cancer surgery. Computed tomography showed a 50-mm middle mediastinal tumor in direct contact with the left and right brachiocephalic veins, aortic arch, and right brachiocephalic artery. Right lateral thoracotomy was performed, and the tumor was resected en bloc with the right brachiocephalic vein and vagal nerve. Recurrence was not observed at 7 years after surgery, even without adjuvant therapy.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Michael Croteau, 21, of Overton, Texas, was diagnosed with pseudomyogenic hemangioendothelioma, an extremely rare cancer that affects just one in one million people.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
CONCLUSIONS This study is the largest population-based study to show the demographic characteristics and analyze the prognosis of OMVT patients. Independent predictors of OS for patients with AS included old age, distant tumor stage, low tumor grade, and surgery. Old age, surgery, and low tumor grade were also predictors of CSS for patients with OAS. Independent predictors of CSS and OS for patients with OHE included old age and surgery. PMID: 31344019 [PubMed - in process]
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This article tries to present the etiopathogenesis, clinical manifestations, diagnosis, treatment and prognosis of P-EHE. 
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Conclusion: FOSB may be fused with SERPINE1, ACTB, or WWTR1 in pseudomyogenic hemangioendotheliomas. The resulting overexpression of FOSB fusion is a potentially useful marker that could be helpful in the diagnosis of these tumors.
Source: Cancer Genomics and Proteomics - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
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