Leucophyllinines A and B, bisindole alkaloids from Leuconotis eugeniifolia

AbstractTwo new bisindole alkaloids, leucophyllinines A (1) and B (2) consisting of eburnane and quebrachamine-type skeletons were isolated from the bark ofLeuconotis eugeniifolia, and their structures were elucidated on the basis of spectroscopic data. Leucophyllinines A and B showed antiplasmodial activities againstPlasmodium falciparum 3D7.
Source: Journal of Natural Medicines - Category: Drugs & Pharmacology Source Type: research