The Effect of Task Modifications on the Fundamental Motor Skills of Boys on the Autism Spectrum: A Pilot Study

This study demonstrates the potential impact that an intervention designed around task modifications can have; however, it also shows that interventions may need to be designed at an individual level and contain the flexibility to adjust to the needs of the child.
Source: Journal of Developmental and Physical Disabilities - Category: Disability Source Type: research

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ConclusionWe reported the genetic and clinical information of 18 RSTS patients from Chinese population with novelCREBBP variants. This study provides a new insight into RSTS and illustrates the value of applying CES which increases the diagnostic yields and enhances the clinical care of RSTS patients.
Source: Molecular Genetics & Genomic Medicine - Category: Genetics & Stem Cells Authors: Tags: ORIGINAL ARTICLE Source Type: research
Conclusion: Fun seeking on the BAS and frustration intolerance should be considered as targets in prevention and intervention programs for IA among adolescents with ADHD.IntroductionThe negative effects of internet addiction (IA) have become a concern in the past decades. IA is characterized by persistent internet use despite negative consequences, loss of control, preoccupation with internet use, increasing amounts of time spent online, and withdrawal symptoms (1). Internet gaming disorders are listed in the “Conditions for Further Study” section in the Fifth Edition of Diagnostic and Statistical Manual of Men...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Kalins Banerjee1, Ni Zhao2, Arun Srinivasan3, Lingzhou Xue3, Steven D. Hicks4, Frank A. Middleton5, Rongling Wu1 and Xiang Zhan1* 1Department of Public Health Sciences, Pennsylvania State University, Hershey, PA, United States2Department of Biostatistics, Johns Hopkins University, Baltimore, MD, United States3Department of Statistics, Pennsylvania State University, University Park, PA, United States4Department of Pediatrics, Pennsylvania State University, Hershey, PA, United States5Department of Neuroscience, State University of New York Upstate Medical University, Syracuse, NY, United States Differential abundance...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Discussion We have found that, in the human genome, the promoter regions of ID-associated genes are uniquely enriched in MER41 LTRs. More specifically, nine ID-associated genes that are putatively important in cognitive evolution exhibit MER41 LTRs in their promoter regions. As more than 100 families of HERV are integrated into our genome, it was important to determine whether our findings are specific to MER41 and to ID-associated genes, and if so to what extent. Among the 133 families of HERV explored here, MER41 is the only family whose LTRs were found with statistically high frequency in the promoter regions of ID-ass...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Conclusions The Cochrane reviews do not provide clear conclusions regarding the effectiveness of TMS and tDCS against adult chronic pain, although small benefits appear to have been observed. However, the authors point out many biases and important heterogeneities of these studies (30). At the moment, it is not possible to establish useful guidelines on the use of TMS and tDCS in the treatment of pediatric migraine and, in general, for pediatric pain treatment. However, adult studies as well as preliminary pediatric reports show that the application of these techniques is safe, with few side effects, potentially low cost...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Fitness is a problem for many people, not least special needs teens and adults. Diabetes and obesity are common in our population.Diet is a factor — it takes a lot of cognitive work to outrun the American junk food industry. The special needs population is vulnerable to deceptive advertising implying health benefits of " sports drinks " .Exercise is also a problem. Special Olympics and Special Hockey programs are low volume — typically once a week. Group classes may be intimidating or unwelcoming. Incomes are low and gyms can be costly [1]. Workout music may be intolerable. The feel and odor of sweat ...
Source: Be the Best You can Be - Category: Disability Tags: adult Asperger ' autism community exercise Source Type: blogs
This study demonstrates the use of Universal Design for Learning (UDL), an educational framework, guidelines, and checklist tools (Eagleton, Universal Design for Learning (UDL), Salem Press, Ipswich,2015; Center for Applied Special Technology, UDL curriculum self-check 2011 (updated 2011),2011.http://udlselfcheck.cast.org/resources.php) to increase accessibility in HIPTeens, an evidence-based sexual risk reduction intervention (Morrison-Beedy et al. in J Assoc Nurses AIDS Care 13(1):21 –27,2002; Res Nurs Health 28(1):3 –15,2005; AIDS Behav 10(5):541,2006; J Assoc Nurses AIDS Care 21(2):153 –161,2010; West...
Source: Sexuality and Disability - Category: Disability Source Type: research
We thank Dr.  Higdon et al. for their interest in our article on metformin and children with autism spectrum disorders (ASD) and for providing information about the MOBILITY study (a Patient-Centered Outcomes Research Institute (PCORI)-funded pragmatic clinical trial to examine the relative effectiveness of me tformin plus healthy lifestyle instruction versus healthy lifestyle instruction alone).1 In our October 2017 article,2 we reported the results of a 16-week open-label extension study of a group of 61 children and adolescents with ASD prescribed second-generation antipsychotic medications (SGAs) who previous...
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Authors: Tags: Letter to the editor Source Type: research
The prevalence of obesity in children with autism spectrum disorder (ASD) exceeds that of the general population, but the level of parental concern about obesity in these children is unexplored.
Source: Disability and Health Journal - Category: Disability Authors: Source Type: research
We report on 2 brothers, aged 7.6 and 20 years, presenting with cognitive impairment, epilepsy, autistic features, hearing loss, and obesity. Array-CGH analysis demonstrated 2 rare CNVs in both siblings: a paternally inherited microdeletion of ∼145 kb at 3p22.1, disrupting theULK4 gene, and a maternally inherited microduplication of ∼117 kb at Xq21.1 including only theBRWD3 gene. As already described for other recurrent syndromes with variable phenotype, these findings are challenging in genetic counseling because of an evident variable penetrance. We discuss the possible correlations between the clinical phenotype...
Source: Cytogenetic and Genome Research - Category: Genetics & Stem Cells Source Type: research
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