Is Bone Loss or Devascularization Associated With Recurrence of Osteomyelitis in Wartime Open Tibia Fractures?

CONCLUSIONS: Recurrent osteomyelitis after open tibia fractures is common. In a univariate model, patients with an intermediate amount of bone loss and those treated with antibiotics for 22 to 56 days were more likely to experience osteomyelitis recurrence. Because only univariate analysis was possible, these findings should be considered preliminary. Osteomyelitis recurrence rates were similar, regardless of initial osteomyelitis classification, indicating that diagnoses of possible osteomyelitis should be treated aggressively.
LEVEL OF EVIDENCE: Level III, therapeutic study.
PMID: 30901004 [PubMed - in process]

Source: Clinical Orthopaedics and Related Research - March 24, 2019 Category: Orthopaedics Authors: Petfield JL, Tribble DR, Potter BK, Lewandowski LR, Weintrob AC, Krauss M, Murray CK, Stinner DJ, Trauma Infectious Disease Outcomes Study Group Tags: Clin Orthop Relat Res Source Type: research