Prevalence of healthcare-associated infections and antimicrobial resistance in Kyiv acute care hospitals, Ukraine

ConclusionsInfection control priorities in hospitals should include preventing surgical site infections, pneumonia, bloodstream infections, and urinary tract infections. These results may help to delineate the requirements for infection prevention and control in acute care hospitals.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research

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This study highlights the need for a better understanding of the complex ecology and dynamics of fluoroquinolone resistance in C. jejuni in poultry environment and warrants an examination of fluoroquinolone-resistant C. jejuni strains recovered from the natural broiler chicken environment.
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
Publication date: Available online 19 February 2020Source: Journal of Molecular BiologyAuthor(s): Madhu Nagaraj, Mumdooh Ahmed, Jeppe Lyngsø, Brian Stougaard Vad, Andreas Bøggild, Anne Fillipsen, Jan Skov Pedersen, Daniel Erik Otzen, Ümit AkbeyAbstractProtein fibrillation is traditionally associated with misfolding, loss of functional phenotype and gain of toxicity in neurodegenerative diseases. However, many organisms exploit fibrils in the form of functional amyloids (FA), as seen in bacteria such as E. coli, Salmonella, Bacillus and Pseudomonas. Here, we provide structural information and mechanistic ...
Source: Journal of Molecular Biology - Category: Molecular Biology Source Type: research
In conclusion, heterogenous clones of optrA-positive LNSEF emerged in the hospital mainly via community-onset. PMID: 32067432 [PubMed - in process]
Source: Annals of Laboratory Medicine - Category: Laboratory Medicine Tags: Ann Lab Med Source Type: research
Authors: Pukai G, Duke T Abstract Background: Acute lower respiratory tract infections are the commonest cause of hospitalisation in young children and supportive care remains the cornerstone of management. A randomised open trial was undertaken at the Port Moresby General Hospital Children's Emergency Department (CED) to determine whether nebulised normal saline had beneficial effects.Methods: Children
Source: Paediatrics and international child health - Category: Pediatrics Tags: Paediatr Int Child Health Source Type: research
Authors: Al-Mnaser AA, Woodward MJ Abstract In vitro studies aimed at studying the mechanism of action of carvacrol and oregano as natural anti-bacterial agents to control multiple antibiotic-resistant avian pathogenic Escherichia coli (APEC) strain O23:H52 isolated from chicken were performed. Derivatives with increased minimum inhibitory concentrations (MIC) to the phytochemicals were selected after growing Escherichia coli (E. coli) strain O23:H52 at sub-lethal concentrations of carvacrol and oregano for a period of 60 days. Whole-genome sequencing (WGS) of two derivatives revealed a missense mutation in cadC an...
Source: Polish Journal of Microbiology - Category: Microbiology Tags: Pol J Microbiol Source Type: research
Publication date: Available online 19 February 2020Source: Journal of the American College of RadiologyAuthor(s): Soheil Kooraki, Melina Hosseiny, Lee Myers, Ali GholamrezanezhadAbstractIn December 2019, a novel coronavirus pneumonia was emerged in Wuhan, China. Since then, this highly contagious coronavirus has been spreading worldwide with a rapid rise in the number of death tolls. The novel coronavirus infected pneumonia (NCIP) is characterized by fever, fatigue, dry cough and dyspnea. A variety of chest imaging features have been reported, similar to those found in other types of coronavirus syndromes. The purpose of t...
Source: Journal of the American College of Radiology - Category: Radiology Source Type: research
ConclusionsInfection control priorities in hospitals should include prevention of surgical site infections, pneumonia, bloodstream infections and urinary tract infections. These results may help to delineate the requirements for infection prevention and control in acute care hospitals.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
Conclusion: Some Lactobacillus strains exhibit anti-CRE activity, which suggests potential applications for controlling or preventing CRE colonization or infection. Introduction Although Enterobacteriaceae are normal flora of the human intestinal system, they are also common pathogens causing human infections in the setting of both community-acquired and healthcare-associated infections (Hsueh et al., 2010; Toh et al., 2012; Lai et al., 2014; Jean et al., 2016). In this era of widespread antibiotic resistance, Enterobacteriaceae are no exception. Recently, the emergence of carbapenem-resistant Enterobacteriaceae (C...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusion This study revealed that Enterococcus species with biofilm potentials and extracellular virulence properties extensively occur in retail RTE shrimps. A significant number of isolated strains are resistant to antibiotics and harbor resistant and virulent genes, denoting a significant route of resistance and virulence dissemination to bacteria in humans. There is an inadequate understanding of the intricacies of antibiotic-resistant enterococci of food origin that belong to enterococci aside from E. faecium and E. faecalis. Findings from this study reveal detailed antibiotic resistance of E. durans, E. casselifla...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
ConclusionsHAIs and increasing antimicrobial resistance present a significant burden to the Ukraine hospital system. Infection control priorities in hospitals should include preventing surgical site infections, respiratory tract infections (which also include PNEU and LRTI), bloodstream infections, and urinary tract infections, as well preventing infections due to antimicrobial-resistant pathogens.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
More News: Antimicrobial Resistance | Enterococcus | Gastroenteritis | Infectious Diseases | Pneumonia | Respiratory Medicine | Staphylococcus Aureus | Ukraine Health | Urinary Tract Infections