Dysregulation of the splicing machinery is associated to the development of non-alcoholic fatty liver disease.

CONCLUSION: There is a close relationship between splicing machinery dysregulation and NAFLD development, which should be further investigated to identify novel therapeutic targets.
PMID: 30901032 [PubMed - as supplied by publisher]

Source: The Journal of Clinical Endocrinology and Metabolism - March 21, 2019 Category: Endocrinology Authors: Del Río-Moreno M, Alors-Pérez E, González-Rubio S, Ferrín G, Reyes O, Rodríguez-Perálvarez M, Sánchez-Frías ME, Sánchez-Sánchez R, Ventura S, López-Miranda J, Kineman RD, de la Mata M, Castaño JP, Gahete MD, Luque RM Tags: J Clin Endocrinol Metab Source Type: research