Comparison between Near-infrared fluorescence imaging with indocyanine green and InfraRed imaging: on-bench trial for kidney perfusion analysis. A project by ESUT-YAUWP group.

CONCLUSIONS: Although NIRF technology with ICG is providing more image detail, we demonstrated that IRT is capable of detecting kidney parenchyma perfusion with warm fluids. Further studies will show its feasibility in graft re-perfusion assessment during kidney transplant or similar applications. PMID: 30895767 [PubMed - as supplied by publisher]
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

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Conclusion: Tacrolimus may be associated with optic neuropathy and PRES at the initial presentation to an ophthalmologist.Case Rep Ophthalmol 2019;10:140 –144
Source: Case Reports in Ophthalmology - Category: Opthalmology Source Type: research
In conclusion, liver transplantation is the only curative procedure for PLD, and the present study indicated that it is relatively and safe and leads to good long-term prognosis and high quality of life. Based on our experience and results, liver transplantation is a primary option for cases of PLD with progressive or advanced symptomatic disease where previous other forms of therapy to palliate symptoms have been insufficient. PMID: 31007749 [PubMed]
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Researchers in Germany have created transparent human organs using a new technology that could pave the way to print three-dimensional body parts such as kidneys for transplants.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
AbstractBackgroundThe interaction between post-transplant anemia (PTA) and allograft function in kidney transplantation has not been evaluated directly. PTA, defined by WHO/AST criteria, was investigated in 1307 adult kidney transplant recipients between 2000 and 2015 (median follow-up, 7  years).MethodsWe investigated the impact of hemoglobin (Hb) on graft failure (non-censored for death) and their interactions, time-dependent Cox model, and subgroup analysis were used.ResultsPTA prevalence was 43.6% at 7  years and varied according to allograft function, recipient sex, and follow-up period. Decreased Hb conside...
Source: Clinical and Experimental Nephrology - Category: Urology & Nephrology Source Type: research
Reena Goswami1, Gayatri Subramanian2, Liliya Silayeva1, Isabelle Newkirk1, Deborah Doctor1, Karan Chawla2, Saurabh Chattopadhyay2, Dhyan Chandra3, Nageswararao Chilukuri1 and Venkaiah Betapudi1,4* 1Neuroscience Branch, Research Division, United States Army Medical Research Institute of Chemical Defense, Aberdeen, MD, United States 2Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States 3Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States 4Department of Physiology and Biophysics, Case Western Reserve University, Clev...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
In this study, we compare the ability of suboptimal doses of freshly sorted and in vitro expanded human CD127loCD25+CD4+ Tregs to promote human skin allograft survival and demonstrate that higher effectiveness of expanded Tregs can be compensated by transient activation of freshly isolated Tregs. Recently-activated Tregs are characterized by an increased expression of Treg functional markers and better in vitro and in vivo survival, correlating with an increased expression of anti-apoptotic BCL-XL. The ability to enhance Treg function without long in vitro culture may be of value in the treatment of specific immunopatholog...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Mauricio Campos-Mora1,2, Pamina Contreras-Kallens1, Felipe Gálvez-Jirón1, Masyelly Rojas1, Carolina Rojas3, Aarón Refisch1, Oscar Cerda2,4 and Karina Pino-Lagos1* 1Centro de Investigación Biomédica, Facultad de Medicina, Universidad de los Andes, Las Condes, Chile 2Programa de Biología Celular y Molecular, Facultad de Medicina, Instituto de Ciencias Biomédicas (ICBM), Universidad de Chile, Santiago, Chile 3Facultad de Odontología, Universidad de Chile, Santiago, Chile 4Millennium Nucleus of Ion Channel Associated Diseases (MiNICAD), Universidad de Chile, San...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Conclusions: Pre-transplantation plasmatic miR-155-5p expression may be useful for stratifying low-immunologic-risk patients, and post-transplantation miR-181a-5p and miR-155-5p may be candidates for inclusion in early, non-invasive prognostic biomarker panels to prevent TCMAR or SCR and better identify patient candidates for IS minimization. Large prospective randomized multicenter trials are needed to refine the cut-off values and algorithms and validate the clinical usefulness of these biomarkers. Introduction Despite great advances in immunosuppressive (IS) therapy, T cell-mediated rejection (TCMAR), which is the...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
IJERPH, Vol. 16, Pages 1453: Factors Correlating to the Development of Hepatitis C Virus Infection in Hemodialysis Patients—Findings Mainly from Asiatic Populations: A Systematic Review and Meta-Analysis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16081453 Authors: Gaofeng Cai Hongjie Zheng Lan Luo Zhengting Wang Zhenggang Jiang Shuangfei Xu Huakun Lv Yongdi Chen Biao Zhou Chonggao Hu Hemodialysis is an effective replacement therapy for chronic renal failure patients. In recent decades, the number of hemodialysis patients has grown rapidly and some me...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
Acute kidney injury (AKI) is a common complication after allogeneic stem cell transplantation (ASCT); however, its incidence and outcome in patients transplanted for multiple myeloma (MM) is unknown. Our results suggest that AKI occurs with low incidence and reduced severity after ASCT for MM. Prophylactic measures in patients with preexisting –kidney failure may further reduce this risk. AbstractAcute kidney injury (AKI) is a common complication after allogeneic stem cell transplantation; however, its incidence and outcome in patients transplanted for multiple myeloma (MM) is unknown. We evaluated the incidence, sev...
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
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