Knockdown of KLF5 promotes cisplatin ‐induced cell apoptosis via regulating DNA damage checkpoint proteins in non‐small cell lung cancer

ConclusionKLF5 plays a significant role in the DNA damage response by regulating DNA damage checkpoint proteins. Inhibition ofKLF5 may be a potential therapeutic target for NSCLC patients with cisplatin resistance.

Source: Thoracic Cancer - March 20, 2019 Category: Cancer & Oncology Authors: Hao Zhang, Fei Shao, Wei Guo, Yibo Gao, Jie He Tags: ORIGINAL ARTICLE Source Type: research