Effect of Serum Deprivation Stress on Signal Induction Regulatory Protein-Alpha (SIRP-Alpha)-Mediated Erythrophagocytosis by Macrophages.

CONCLUSIONS Serum deprivation and LPS/INF-Gamma induction resulted in increased SIRP-alpha expression and erythrophagocytosis. Using SIRP-alpha Ab during this condition decreased the rate of erythrophagocytosis, which indicates that SIRP-alpha receptor can have pro-phagocytic activity.
PMID: 30894504 [PubMed - in process]

Source: Methods of Information in Medicine - March 20, 2019 Category: Information Technology Authors: Hindi Z, Gad A, Jarvis C, Zahoor T, Spellman C, Filleur S Tags: Med Sci Monit Basic Res Source Type: research