Diabetes drug alters vitamin D levels, possibly explaining increased bone fracture risk

Scientists found that the diabetes drug canagliflozin reduces vitamin D levels and calcium uptake, which may explain why this drug can increase the risk of bone fractures. 
Source: NIDDK News - Category: Endocrinology Source Type: news

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Conclusion Results may assist clinicians in aiming exercise programs toward increasing hip and potentially core strength, thus improving balance to promote better mobility for individuals with a lower-limb amputation.
Source: JPO Journal of Prosthetics and Orthotics - Category: Orthopaedics Tags: CME ARTICLES Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
New meta-analysis shows that radioactive iodine treatment for hyperthyroidism doesn't significantly increase cancer risk or cancer mortality in the vast majority of cases.Medscape Medical News
Source: Medscape Hematology-Oncology Headlines - Category: Cancer & Oncology Tags: Diabetes & Endocrinology News Source Type: news
Conditions:   Pre Diabetes;   Exercise;   Metformin;   Atherosclerosis Intervention:   Behavioral: Exercise Sponsor:   Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
A biofilm is a highly organized community of microorganisms that develops naturally on certain surfaces. Typically, biofilms are made up of microbes and an extracellular matrix that they produce. This matrix can include polysaccharides (chains of sugars), proteins, lipids, DNA, and other molecules. The matrix gives the biofilm structure and helps it stick to a surface. Formation of a biofilm often involves a process called quorum sensing. In this process, microbes detect when they reach a certain population density and change their behavior in ways that help them function as a community. Biofilms are common and h...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - Category: Research Authors: Tags: Cells Injury and Illness Bacteria Biofilms Microbes Source Type: blogs
Conclusions: Patients with post-bulbar ulcers have a poorer prognosis than those with bulbar ulcers. After the diagnosis of hemorrhagic post-bulbar duodenal ulcer, close follow-up is necessary.Digestion
Source: Digestion - Category: Gastroenterology Source Type: research
Obesity (Silver Spring). 2021 Sep 21. doi: 10.1002/oby.23249. Online ahead of print.ABSTRACTDysregulation of hepatic glucose production (HGP) and glucose disposal leads to hyperglycemia and type 2 diabetes. Hyperglycemia results from the declining ability of insulin to reduce HGP and increase glucose disposal, as well as inadequate ß-cell compensation for insulin resistance. Hyperglucagonemia resulting from reduced suppression of glucagon secretion by insulin contributes to hyperglycemia by stimulating HGP. The actions of pancreatic hormones are normally complemented by peptides secreted by cells distributed througho...
Source: Obesity - Category: Eating Disorders & Weight Management Authors: Source Type: research
Chronobiol Int. 2021 Sep 21:1-8. doi: 10.1080/07420528.2021.1966026. Online ahead of print.ABSTRACTEmerging research suggests that sleep contributes to racial disparities in cardiovascular disease (CVD). Racial/ethnic minorities are disproportionately affected by poor cardiovascular outcomes including obesity, hypertension and diabetes. Although circadian rhythms affect sleep patterns, few studies have examined disparities in circadian health or the contribution of circadian disparities to CVD. In this paper, we provide an overview of the relation between circadian health and CVD in the context of health disparities. We di...
Source: Chronobiology International - Category: Biology Authors: Source Type: research
CONCLUSION: Focus group themes highlighted that this intervention may empower individuals to feel confident in their choices and attain their goals during their health and wellness journey.PMID:34547985 | DOI:10.1080/17482631.2021.1978373
Source: International Journal of Qualitative Studies on Health and Well-being - Category: International Medicine & Public Health Authors: Source Type: research
In 1989, Barker et al reported a correlation between lower birth weights and increased risk for death in adulthood from ischemic heart disease in men born between 1911-1930 in England (Lancet 1989;2:577-80. doi: https://doi.org/10.1016/s0140-6736(89)90710-1). Many subsequent studies have affirmed the relationship between birth weight and conditions such as diabetes, hypertension, and obesity. In this volume of The Journal of Pediatrics, Lilja et al report an association between birth weight and stroke in adulthood.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: The Editors' Perspectives Source Type: research
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