Copper sulfide: an emerging adaptable nanoplatform in cancer theranostics

This article discusses the pros and cons of using CuS NPs in diagnostics, therapeutics, and theranostics. The first section introduces CuS NPs and discusses the features that render them more advantageous than other established nanoplatforms in cancer management. Subsequent sections include specific in vitro and in vivo results of different studies showing the potential of CuS NPs as nanoplatforms. Methods used for visualization (photoacoustic imaging and magnetic resonance imaging) of CuS NPs and treatment (phototherapy and combinatorial therapy) have also been discussed. Furthermore, the challenges and opportunities associated with using CuS NPs have been elucidated. Further investigations on CuS NPs are required to translate it for clinical applications.Graphical abstract
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research

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ConclusionCurettage for miscarriage or undesired pregnancy is not exempt from complications, such as hemorrhage, simple perforation, and infection. Intrauterine fallopian tube incarceration is uncommon but can affect fertility. This diagnosis is important to avoid destruction of the fimbriae and necrosis of the tube and also to reduce the risk of ectopic pregnancy.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Conditions:   MRI Guided Transurethral Ultrasound Ablation;   Localized Prostate Cancer;   Ablation Therapy Intervention:   Procedure: Magnetic Resonance Imaging-Guided Transurethral Ultrasound Ablation of Prostate Tissue Sponsor:   University Hospital, Strasbourg, France Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsAI models based on textural features of MR images of patients with LARC may help to identify patients who will show CR at the end of treatment and those who will not respond to therapy (NR) at an early stage of the treatment.
Source: European Journal of Radiology - Category: Radiology Source Type: research
ConclusionsThe ability of Na[18F]F/[18F]FDG PET/MRI to identify more skeletal lesions than99mTc-MDP WBBS and to additionally identify extra-skeletal disease may be beneficial for patient care and represent an alternative to the single modalities performed separately. Na[18F]F/[18F]FDG PET/MRI is a promising approach for evaluation of skeletal and extra-skeletal lesions in a selected population of breast and prostate cancer patients.
Source: Molecular Imaging and Biology - Category: Molecular Biology Source Type: research
Magnetic Resonance Imaging detects breast cancer at earlier stages than mammography, according to a  studyrecently published inOncology.Around 15 percent of women with breast cancer were diagnosed despite having no causative hereditary gene mutation but had a family history of breast cancer. To better understand diagnosis rates, researchers from Erasmus University in the Netherlands implemented a randomized controlled trial (FaMRIsc) throughout 12 hospitals in the Netherlands to compare the efficacy of MRI screening against mammography in women with a family history of breast cancer.The study took place between Januar...
Source: radRounds - Category: Radiology Authors: Source Type: blogs
Using magnetic resonance imaging in tandem with the traditional ultrasound method can significantly improve prostate cancer detection, according to a  study recently published inJAMA Surgery.Prostate cancer has been traditionally diagnosed with only ultrasound. Physicians use the technique for tissue biopsy. However, this method alone can ’t detect certain tumors. Historically, MRI-based biopsy practices are practical because they can detect precise lesions on the prostate. Yet, not all tumors appear on MRI, making it difficult to identify all kinds of cancer. Researchers from the University of California Los An...
Source: radRounds - Category: Radiology Authors: Source Type: blogs
Multiparametric (mp) prostate magnetic resonance imaging (MRI) is playing an increasingly prominent role in the diagnostic work-up of patients with suspected prostate cancer. Performing mpMRI before biopsy offers several advantages including biopsy avoidance under certain clinical circumstances and targeting biopsy of suspicious lesions to enable the correct diagnosis. The success of the technique is heavily dependent on high-quality image acquisition, interpretation, and report communication, all areas addressed by previous versions of the Prostate Imaging-Reporting and Data System (PI-RADS) recommendations.
Source: Clinical Radiology - Category: Radiology Authors: Tags: Review Source Type: research
We present the case of a 43-year-old female diagnosed with a pancreatobiliary maljunction and an associated stenosis of the bile duct, secondary to an episode of acute pancreatitis. She underwent several endoscopic retrograde cholangiopancreatography procedures over the course of three years, without improvement of the stenosis, and therefore a surgical approach was taken. Prior to the surgical intervention, magnetic resonance imaging showed the presence of an 11-mm polyp in the gallbladder. A histological study of the surgical sample identified intramucosal adenocarcinoma over a tubular adenoma of the gallbladder. Pancrea...
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
Not long ago, an abnormal PSA reading would be followed right away by a standard biopsy to search for potential cancer in the prostate. During such a procedure, doctors take 10 to 12 samples of the prostate from various locations while looking at the gland with an ultrasound machine. These days, however, men with high PSA levels during cancer screening might be offered a specialized imaging test first. Called a multiparametric magnetic resonance imaging (mpMRI) scan, it’s particularly good at visualizing cancer in the prostate and distinguishing high-grade tumors that need immediate treatment from low-grade tumors th...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Diagnosis Prostate Knowledge Screening HPK Source Type: blogs
Conclusions The deep learning protocol showed accuracy comparable to current radiographic criteria. Computer-aided frameworks could be implemented as aids for radiologists to identify high-risk IPMN.
Source: Pancreas - Category: Gastroenterology Tags: Original Articles Source Type: research
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